ZETA

Pronunciation (US):

(GB):

IPA (US):

 Dictionary entry overview: What does zeta mean? 

• ZETA (noun)
  The noun ZETA has 1 sense:

1. the 6th letter of the Greek alphabet

  Familiarity information: ZETA used as a noun is very rare.

 Dictionary entry details 

• ZETA (noun)

Sense 1

Meaning:

The 6th letter of the Greek alphabet

Classified under:

Nouns denoting communicative processes and contents

Hypernyms ("zeta" is a kind of...):

alphabetic character; letter; letter of the alphabet (the conventional characters of the alphabet used to represent speech)

Holonyms ("zeta" is a member of...):

Greek alphabet (the alphabet used by ancient Greeks)

 Context examples 

Upon administration, autologous PBTL CD19CAR-28 zeta may stimulate host cytotoxic T lymphocyte (CTL) and antibody responses against CD19-expressing tumor cells, resulting in tumor cell lysis.

(Autologous PBTL CD19CAR-28 zeta, NCI Thesaurus)

Its inclusion may also increase antitumor activity, when compared to the inclusion of the CD3-zeta chain alone.

(Anti-CD19-CAR-CD3zeta-4-1BB-Expressing Allogenic Natural Killer Cells, NCI Thesaurus)

Furthermore, inclusion of the 4-1BB signaling domain may increase the antitumor activity compared to the inclusion of the CD28 costimulatory domain and TCR zeta chain alone.

(Autologous PBTL CD19CAR-28/CD137/zeta, NCI Thesaurus)

The chimeric IgCD28TCR gene consists of portions of CD28, the zeta chain of the T-cell receptor (TCRzeta), and a single chain antibody domain (sFv) specific for the tumor-associated antigen CEA.

(Anti-CEA IgCD28TCR-Transduced Autologous T Cells, NCI Thesaurus)

CD3 zeta is one of several membrane-bound polypeptides found in the TCR/CD3 complex, which regulates both the assembly of complete TCR complexes and their expression on the cell surface.

(Anti-CD19-CAR Retroviral Vector-Transduced Autologous T Cells, NCI Thesaurus)

The inclusion of the CD28 signaling domain may increase proliferation of T-cells and antitumor activity compared to the inclusion of the CD3-zeta chain alone.

(Autologous CD19-28z Chimeric Antigen Receptor-expressing T-lymphocytes, NCI Thesaurus)

CD3-zeta (or CD247) is a transmembrane signaling adaptor polypeptide that regulates the assembly of complete TCR complexes and their expression on the cell surface.

(CD19CAR-CD3zeta-4-1BB-expressing Autologous T-lymphocytes, NCI Thesaurus)

Autologous EBV-CTL CD19CAR zeta directs the T-lymphocytes to CD19-expressing tumor cells, stimulating a selective toxicity to tumor cells.

(Autologous EBV-CTL CD19CAR zeta, NCI Thesaurus)

The anti-mesothelin mRNA encodes a single chain antibody variable fragment (ScFv), the intracellular CD 3 zeta T cell receptor domain and the 4-1BB (cd137) costimulatory domain.

(Anti-mesothelin CIR mRNA-electroporated Autologous T Cells, NCI Thesaurus)

CD3 zeta is one of several membrane-bound polypeptides found in the T-cell receptor (TCR)/CD3 complex and regulates the assembly of complete TCR complexes and their expression on the cell surface.

(Anti-CD20-CAR-CD3zeta-4-1BB-expressing Autologous T-lymphocyte Cells, NCI Thesaurus)