VINCA

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 Dictionary entry overview: What does Vinca mean? 

• VINCA (noun)
  The noun VINCA has 1 sense:

1. periwinkles: low creeping evergreen perennials

  Familiarity information: VINCA used as a noun is very rare.

 Dictionary entry details 

• VINCA (noun)

Sense 1

Meaning:

Periwinkles: low creeping evergreen perennials

Classified under:

Nouns denoting plants

Synonyms:

genus Vinca; Vinca

Hypernyms ("Vinca" is a kind of...):

dicot genus; magnoliopsid genus (genus of flowering plants having two cotyledons (embryonic leaves) in the seed which usually appear at germination)

Meronyms (members of "Vinca"):

periwinkle (chiefly trailing poisonous plants with blue flowers)

Holonyms ("Vinca" is a member of...):

Apocynaceae; dogbane family; family Apocynaceae (chiefly tropical trees or shrubs or herbs having milky juice and often showy flowers; many are sources of drugs)

 Context examples 

Mediated through its folate moiety, folate receptor-targeted vinca alkaloid EC0489 delivers the cytotoxic vinca alkaloid moiety directly to cells expressing folic acid receptors, frequently upregulated in many types of tumor cells.

(Folate Receptor-Targeted Vinca Alkaloid EC0489, NCI Thesaurus)

Hemiasterlin analog E7974 binds to the Vinca domain on tubulin, resulting in inhibition of tubulin polymerization and microtubule assembly; depolymerization of existing microtubules; inhibition of mitosis; and inhibition of cellular proliferation.

(Hemiasterlin Analog E7974, NCI Thesaurus)

Eribulin binds to the vinca domain of tubulin and inhibits both the polymerization of tubulin and the assembly of microtubules.

(Liposomal Eribulin Mesylate, NCI Thesaurus)

A formulation of the semisynthetic vinca alkaloid, vinorelbine, encapsulated within liposomes, with antineoplastic activity.

(Liposomal Vinorelbine, NCI Thesaurus)

It is a type of vinca alkaloid and a type of antimitotic agent.

(Liposomal vincristine sulfate, NCI Dictionary)

Unlike other tubulin inhibitors such as the taxanes and vinca alkaloids, noscapine does not affect microtubule polymerization.

(Noscapine Hydrochloride, NCI Thesaurus)

Indibulin binds to a site on tubulin that is different from taxane- or Vinca alkaloid-binding sites, destabilizing tubulin polymerization and inducing tumor cell cycle arrest and apoptosis.

(Indibulin, NCI Thesaurus)

Folate receptor-targeted vinca alkaloid/mitomycin C EC0225 contains two potent cytotoxic agents, a vinca alkaloid and mitomycin C, linked to a single folate molecule.

(Folate Receptor-Targeted Vinca Alkaloid/Mitomycin C EC0225, NCI Thesaurus)

Dofequidar has demonstrated reversal of the MDR phenotype in those cells exposed to various chemotherapeutic agents, such as vinca alkaloids and anthracyclines.

(Dofequidar Fumarate, NCI Thesaurus)

A semisynthetic derivative of the vinca alkaloid vinblastine, with potential antineoplastic activity.

(Anhydrovinblastine, NCI Thesaurus)