VASOPRESSOR

Pronunciation (US):

(GB):

 Dictionary entry overview: What does vasopressor mean? 

• VASOPRESSOR (noun)
  The noun VASOPRESSOR has 1 sense:

1. any agent that produces vasoconstriction and a rise in blood pressure (usually understood as increased arterial pressure)

  Familiarity information: VASOPRESSOR used as a noun is very rare.

 Dictionary entry details 

• VASOPRESSOR (noun)

Sense 1

Meaning:

Any agent that produces vasoconstriction and a rise in blood pressure (usually understood as increased arterial pressure)

Classified under:

Nouns denoting man-made objects

Hypernyms ("vasopressor" is a kind of...):

pressor; vasoconstrictive; vasoconstrictor (any agent that causes a narrowing of an opening of a blood vessel: cold or stress or nicotine or epinephrine or norepinephrine or angiotensin or vasopressin or certain drugs; maintains or increases blood pressure)

 Context examples 

Enalaprilat prevents the conversion of angiotensin I into angiotensin II by inhibiting ACE, thereby leading to decreased vasopressor activity and resulting in vasodilation.

(Enalaprilat, NCI Thesaurus)

Lisinopril, a synthetic peptide derivative, specifically and competitively inhibits ACE, which results in a decrease in the production of the potent vasoconstrictor angiotensin II and, so, diminished vasopressor activity.

(Lisinopril, NCI Thesaurus)

Fosinoprilat specifically and competitively inhibits angiotensin-converting enzyme thereby decreasing the formation of the potent vasoconstrictor angiotensin II, resulting in diminished vasopressor activity.

(Fosinopril, NCI Thesaurus)

Expressed in liver by human AGT Gene (Serpin Family), secreted 485-aa 53-kDa Angiotensinogen is cleaved by renin (in response to lowered blood pressure) to inactive decapeptide Angiotensin I, which is cleaved by ACE to generate active octapeptide vasopressor Angiotensin II (maintains blood pressure and regulates the volume and mineral balance of body fluids).

(Angiotensin, NCI Thesaurus)

Cardiogenic shock is defined as a sustained (greater than30 minutes) episode of systolic blood pressure less than90 mm Hg, and/or cardiac index less than2.2 L/min/m2 determined to be secondary to cardiac dysfunction, and/or the requirement for parenteral inotropic or vasopressor agents or mechanical support (e.g., Intra aortic balloon pump (IABP), extracorporeal circulation, ventricular assist devices) to maintain blood pressure and cardiac index above those specified levels.

(Cardiogenic Shock, NCI Thesaurus/CDISC)