UNREGULATED

Pronunciation (US):

(GB):

IPA (US):

 Dictionary entry overview: What does unregulated mean? 

• UNREGULATED (adjective)
  The adjective UNREGULATED has 2 senses:

1. not regulated; not subject to rule or discipline

2. without regulation or discipline

  Familiarity information: UNREGULATED used as an adjective is rare.

 Dictionary entry details 

• UNREGULATED (adjective)

Sense 1

Meaning:

Not regulated; not subject to rule or discipline

Context example:

unregulated off-shore fishing

Antonym:

regulated (controlled or governed according to rule or principle or law)

Sense 2

Meaning:

Without regulation or discipline

Context example:

an unregulated environment

Similar:

unstructured (lacking definite structure or organization)

 Context examples 

Insertion of the provirus can cause mutations by interrupting coding sequences or regulatory elements, or cause unregulated expression of the proto-oncogene resulting in tumor formation.

(Insertional Mutagenesis, NLM, Medical Subject Headings)

Reciprocal t(17;22)(q22;q13) translocations with COL1A1 result in unregulated growth factor expression and are associated with DFSP.

(Oncogene SIS, NCI Thesaurus)

The unregulated growth of cancer cells insofar as growth control and contact inhibition.

(Cancer Cell Growth, NCI Thesaurus)

The kinase activity of Abl in the bcr-abl fusion is activated and unregulated, driving the uncontrolled cell growth observed in CML.

(Inhibition of Cellular Proliferation by Gleevec Pathway, NCI Thesaurus/BIOCARTA)

The interaction of multiple different factors in cyclin E accumulation integrates different signaling pathways with cell cycle regulation and may play a role in the unregulated cell cycle progression of cancer.

(Cyclin E Degradation Pathway, NCI Thesaurus/BIOCARTA)

A new formation of tissue that does not subserve a physiologic purpose, has unregulated growth, exhibits cellular characteristics resembling cells of gastrointestinal lineage, and grows autonomously.

(Neoplasms of the Mouse Intestinal Tract, NCI Thesaurus/MMHCC)

Reciprocal translocations between chromosomes 17 and 22, where this gene and the gene for platelet-derived growth factor beta are located, are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans, resulting from unregulated expression of the growth factor.

(Collagen I (Alpha 1), NCI Thesaurus/LocusLink)