TRYPTOPHAN

Pronunciation (US):

(GB):

 Dictionary entry overview: What does tryptophan mean? 

• TRYPTOPHAN (noun)
  The noun TRYPTOPHAN has 1 sense:

1. an amino acid that occurs in proteins; is essential for growth and normal metabolism; a precursor of niacin

  Familiarity information: TRYPTOPHAN used as a noun is very rare.

 Dictionary entry details 

• TRYPTOPHAN (noun)

Sense 1

Meaning:

An amino acid that occurs in proteins; is essential for growth and normal metabolism; a precursor of niacin

Classified under:

Nouns denoting substances

Synonyms:

tryptophan; tryptophane

Hypernyms ("tryptophan" is a kind of...):

essential amino acid (an amino acid that is required by animals but that they cannot synthesize; must be supplied in the diet)

 Context examples 

D-1MT blocks the breakdown of the amino acid tryptophan, which is needed for T cells (a type of immune system cell) to kill tumor cells.

(D-1MT, NCI Dictionary)

This gene plays a role in the metabolism of fatty acids, tryptophan, drugs and xenobiotics.

(CYP2C18 Gene, NCI Thesaurus)

INCB024360 targets and binds to IDO1, an enzyme responsible for the oxidation of tryptophan into kynurenine.

(IDO1 Inhibitor INCB024360, NCI Thesaurus)

An orally bioavailable synthetic peptide containing the amino acids D-glutamine and L-tryptophan connected by a gamma-glutamyl linkage with potential immunostimulating, antimicrobial and antineoplastic activities.

(Golotimod, NCI Thesaurus)

It is characterized by abnormalities in the metabolism of lysine, hydroxylysine, and tryptophan that result in the accumulation and urinary excretion of glutaric acid.

(Glutaric Acidemia Type 1, NCI Thesaurus)

This gene is involved in the metabolism of the amino acid tryptophan.

(INDO Gene, NCI Thesaurus)

This allele, which encodes indoleamine 2,3-dioxygenase protein, plays a role in tryptophan metabolism.

(INDO wt Allele, NCI Thesaurus)

This protein is involved in the degradation of tryptophan.

(Indoleamine 2,3-Dioxygenase, NCI Thesaurus)

The disodium salt of a synthetic form of a naturally-occurring dipeptide consisting of L-glutamic acid and L-tryptophan with potential antiangiogenic and potential immunomodulating activities.

(Oglufanide Disodium, NCI Thesaurus)

Numerous studies have searched for a potential genetic role of tryptophan hydroxylase mutations in neuropsychiatric indications, with conflicting results.

(Neurotransmitter Biosynthesis Pathway, NCI Thesaurus/BIOCARTA)