TRANSFORMING GENE

Pronunciation (US):

(GB):

IPA (US):

 Dictionary entry overview: What does transforming gene mean? 

• TRANSFORMING GENE (noun)
  The noun TRANSFORMING GENE has 1 sense:

1. a gene that disposes normal cells to change into cancerous tumor cells

  Familiarity information: TRANSFORMING GENE used as a noun is very rare.

 Dictionary entry details 

• TRANSFORMING GENE (noun)

Sense 1

Meaning:

A gene that disposes normal cells to change into cancerous tumor cells

Classified under:

Nouns denoting body parts

Synonyms:

oncogene; transforming gene

Hypernyms ("transforming gene" is a kind of...):

cistron; factor; gene ((genetics) a segment of DNA that is involved in producing a polypeptide chain; it can include regions preceding and following the coding DNA as well as introns between the exons; it is considered a unit of heredity)

 Context examples 

A transforming gene activated in certain human B lymphoid tumors, B-lym was originally detected by transfection of NIH 3T3 cells with DNA from Burkitt lymphomas.

(Oncogene B-LYM, NCI Thesaurus)

Originally identified in the Rous sarcoma virus src transforming gene, Non-Receptor Tyrosine Kinase Genes encode Protein Tyrosine Kinases, enzymes important in control of cell growth, proliferation, differentiation, and transformation that do not function as receptors, but catalyze tyrosine phosphorylation of proteins with ATP, or other nucleotides as phosphate donors.

(Non-Receptor Tyrosine Kinase Gene, NCI Thesaurus)