English Dictionary |
TRANSCRIPTASE
Pronunciation (US): | (GB): |
Dictionary entry overview: What does transcriptase mean?
• TRANSCRIPTASE (noun)
The noun TRANSCRIPTASE has 1 sense:
1. the enzyme that copies DNA into RNA
Familiarity information: TRANSCRIPTASE used as a noun is very rare.
Dictionary entry details
Sense 1
Meaning:
The enzyme that copies DNA into RNA
Classified under:
Nouns denoting substances
Synonyms:
RNA polymerase; transcriptase
Hypernyms ("transcriptase" is a kind of...):
polymerase (an enzyme that catalyzes the formation of new DNA and RNA from an existing strand of DNA or RNA)
Context examples
The incorporation of the activated triphosphate metabolite of entecavir inhibits the reverse transcriptase (RT) viral RNA-dependent HBV DNA polymerase and, so, the replication of viral DNA and transcription.
(Entecavir, NCI Thesaurus)
Capravirine shows antiviral activity against wild-type HIV as well as HIV strains with mutations in reverse transcriptase.
(Capravirine, NCI Thesaurus)
A synthetic non-nucleoside reverse transcriptase (RT) inhibitor with antiviral activity.
(Efavirenz, NCI Thesaurus)
A viral reverse transcriptase is bound to the 5' extremity of the long strand.
(hepatitis B virus, NCI Thesaurus)
Mechanisms to suppress growth include inhibition of cell wall synthesis; increased cell wall permeability; protein synthesis inhibition; and inhibition of reverse transcriptase and protease.
(Antimicrobial Effect, NCI Thesaurus)
A substance structurally unlike a nucleoside molecule that is capable of inhibiting the function of a reverse transcriptase.
(Non-nucleoside Reverse Transcriptase Inhibitor, NCI Thesaurus)
Following amplification of reverse transcriptase polymerase chain reaction assay, the quantified amount of the target gene divided by the quantified amount of housekeeping gene.
(Normalized Quotient, NCI Thesaurus)
A dideoxyuridine inhibitor of HIV reverse transcriptase that is related to zidovudine.
(Navuridine, NCI Thesaurus)
Emivirine has a structure typical of a nucleoside analog but has been shown to bind directly to the reverse transcriptase and act as an NNRTI.
(Emivirine, NCI Thesaurus)
A nucleoside reverse transcriptase inhibitor analog of adenosine.
(Didanosine, NCI Thesaurus)
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