TRANSAMINASE

Pronunciation (US):

(GB):

 Dictionary entry overview: What does transaminase mean? 

• TRANSAMINASE (noun)
  The noun TRANSAMINASE has 1 sense:

1. a class of transferases that catalyze transamination (that transfer an amino group from an amino acid to another compound)

  Familiarity information: TRANSAMINASE used as a noun is very rare.

 Dictionary entry details 

• TRANSAMINASE (noun)

Sense 1

Meaning:

A class of transferases that catalyze transamination (that transfer an amino group from an amino acid to another compound)

Classified under:

Nouns denoting substances

Synonyms:

aminopherase; aminotransferase; transaminase

Hypernyms ("transaminase" is a kind of...):

transferase (any of various enzymes that move a chemical group from one compound to another compound)

Hyponyms (each of the following is a kind of "transaminase"):

glutamic oxalacetic transaminase; glutamic oxaloacetic transaminase (an enzyme involved in transamination)

 Context examples 

Liver function tests include the measurement of albumin, alanine transaminase, aspartate transaminase, alkaline phosphatase, bilirubin, and gamma glutamyl transferase.

(Liver function test, NCI Thesaurus)

A high level of aspartate transaminase released into the blood may be a sign of liver or heart damage, cancer, or other diseases.

(Aspartate transaminase, NCI Dictionary)

Also called serum glutamate pyruvate transaminase and SGPT.

(Alanine transferase, NCI Dictionary)

Severe inability of the liver to function normally, as evidenced by severe jaundice and abnormal levels of ammonia, bilirubin, alkaline phosphatase, glutamic oxaloacetic transaminase, lactic dehydrogenase, and reversal of the albumin/globulin ratio.

(Liver Failure, NLM, Medical Subject Headings)

Aspartate is then transaminated by aspartate transaminase to exchange its amino group onto alpha-ketoglutarate and be converted into oxaloacetate.

(Catabolic Pathway for Asparagine and Aspartate, NCI Thesaurus/BIOCARTA)

This agent binds to and inhibits gamma-aminobutyric acid (GABA) transaminase and its anticonvulsant activity may be exerted by increasing brain concentration of GABA and by inhibiting enzymes that catabolize GABA or block the reuptake of GABA into glia and nerve endings.

(Divalproex Sodium, NCI Thesaurus)

Severe preeclampsia associated with any of the following findings: thrombocytopenia (platelets less than 100,000 per microliter), impaired liver function (twice normal elevation of hepatic transaminases; severe, persistent right upper quadrant or epigastric pain), progressive renal insufficiency (serum creatinine greater than 1.1 mg/dL or doubling of baseline in the absence of other renal disease), pulmonary edema, or new-onset cerebral or visual disturbances.

(HELLP Syndrome, NCI Thesaurus)

Also called serum glutamic-oxaloacetic transaminase and SGOT.

(Aspartate transaminase, NCI Dictionary)