TOXICITY

Pronunciation (US):

(GB):

IPA (US):

 Dictionary entry overview: What does toxicity mean? 

• TOXICITY (noun)
  The noun TOXICITY has 2 senses:

1. the degree to which something is poisonous

2. grave harmfulness or deadliness

  Familiarity information: TOXICITY used as a noun is rare.

 Dictionary entry details 

• TOXICITY (noun)

Sense 1

Meaning:

The degree to which something is poisonous

Classified under:

Nouns denoting quantities and units of measure

Hypernyms ("toxicity" is a kind of...):

definite quantity (a specific measure of amount)

Hyponyms (each of the following is a kind of "toxicity"):

cytotoxicity (the degree to which something is toxic to living cells)

Derivation:

toxic (of or relating to or caused by a toxin or poison)

Sense 2

Meaning:

Grave harmfulness or deadliness

Classified under:

Nouns denoting attributes of people and objects

Synonyms:

perniciousness; toxicity

Hypernyms ("toxicity" is a kind of...):

morbidity; morbidness; unwholesomeness (the quality of being unhealthful and generally bad for you)

 Context examples 

Bromacrylide has been shown to decrease tumor growth in animal models, but is accompanied with severe toxicity, including severe bone marrow suppression and weight loss.

(Bromacrylide, NCI Thesaurus)

Compared to LPS, MPLA exerts a similar immunostimulatory activity but with reduced toxicity.

(Monophosphoryl Lipid A, NCI Thesaurus)

Acquired causes include diabetes, uremia, hepatic disorders, vitamin deficiencies, toxins, and drug toxicities.

(Autonomic Neuropathy, NCI Thesaurus)

Upon transfusion, autologous PBTL CD19CAR-28/CD137zeta directs the T-lymphocytes to CD19-expressing tumor cells and induces selective toxicity in CD19-expressing tumor cells.

(Autologous PBTL CD19CAR-28/CD137/zeta, NCI Thesaurus)

The dimer configuration has been shown to increase compound stability and reduce general toxicity.

(Artemisinin Dimer, NCI Thesaurus)

Autologous EBV-CTL CD19CAR zeta directs the T-lymphocytes to CD19-expressing tumor cells, stimulating a selective toxicity to tumor cells.

(Autologous EBV-CTL CD19CAR zeta, NCI Thesaurus)

Agents administered before, with, or after cancer therapy to reduce or prevent damage or toxicity to the kidney.

(Nephroprotective Agent, NCI Thesaurus)

Most common breed utilized in biomedical research and is used in a variety of studies including developmental toxicity studies, toxicology studies, asthma research, and antibody production.

(New Zealand White Rabbit, NCI Thesaurus)

A liposomal formulation of doxorubicin also modulates toxicity, specifically the cardiac effects commonly seen with anthracycline antitumor drugs.

(Pegylated Liposomal Doxorubicin Hydrochloride, NCI Thesaurus)

Pegylated liposomal delivery of irinotecan improves drug penetration into tumors and decreases drug clearance, thereby increasing the duration of exposure while lowering systemic toxicity.

(Pegylated Liposomal Irinotecan, NCI Thesaurus)