THYMINE

Pronunciation (US):

(GB):

 Dictionary entry overview: What does thymine mean? 

• THYMINE (noun)
  The noun THYMINE has 1 sense:

1. a base found in DNA (but not in RNA) and derived from pyrimidine; pairs with adenine

  Familiarity information: THYMINE used as a noun is very rare.

 Dictionary entry details 

• THYMINE (noun)

Sense 1

Meaning:

A base found in DNA (but not in RNA) and derived from pyrimidine; pairs with adenine

Classified under:

Nouns denoting substances

Synonyms:

T; thymine

Hypernyms ("thymine" is a kind of...):

pyrimidine (any of several basic compounds derived from pyrimidine)

Holonyms ("thymine" is a substance of...):

deoxyribonucleic acid; desoxyribonucleic acid; DNA ((biochemistry) a long linear polymer found in the nucleus of a cell and formed from nucleotides and shaped like a double helix; associated with the transmission of genetic information)

 Context examples 

DNA is a long molecule made by stringing 4 chemical bases together: adenine (A), guanine (G), cytosine (C), and thymine (T).

(Expanding the Genetic Alphabet, NIH)

G/T mismatch-specific thymine DNA glycosylase (410 aa, ~46 kDa) is encoded by the human TDG gene.

(G/T Mismatch-Specific Thymine DNA Glycosylase, NCI Thesaurus)

Distamycin antibiotics bind to the minor groove of DNA, preferentially to adenine-thymine (A-T) rich sequences, thereby inhibiting DNA replication and RNA transcription.

(Distamycin Antineoplastic Antibiotic, NCI Thesaurus)

Duocarmycin antibiotics alkylate DNA by binding to adenine-thymine (A-T)- rich sequences in the minor groove of DNA, thereby inhibiting DNA replication and inducing apoptosis.

(Duocarmycin Antineoplastic Antibiotic, NCI Thesaurus)

Unmethylated cytosines will be displayed as cytosines in the control sample and as thymines in the bisulfite-treated sample.

(Bisulfite Sequencing, NCI Thesaurus)

This stain preferentially binds to the phosphate groups of DNA and aggregates at areas with an increase in adenine-thymine binding, thus leading to chromosomal staining patterns that lend themselves to g-banding analysis.

(Giemsa Staining Method, NCI Thesaurus)

Nucleotide Excision Repair (NER) mends DNA regions that contain chemical adducts, such as UV-induced thymine dimers or carcinogenic adducts, which distort the DNA helix and interfere with replication and transcription.

(Nucleotide Excision Repair, NCI Thesaurus)

As a thymidylate synthase inhibitor, OSI-7904 noncompetitively binds to thymidylate synthase, resulting in inhibition of thymine nucleotide synthesis and DNA replication.

(OSI-7904L, NCI Thesaurus)

Activated by carboxyl esterase, pibrozelesin alkylates DNA by binding to adenine-thymine (A-T)-rich sequences in the minor groove of DNA, thereby inhibiting DNA replication and inducing apoptosis.

(Pibrozelesin, NCI Thesaurus)

Nucleotide Excision Repair (NER) Inhibition involves interference with, or restraint of, the activities that mend DNA regions containing chemical adducts, carcinogenic adducts, or thymine dimers.

(Nucleotide Excision Repair Inhibition, NCI Thesaurus)