THYMIDINE

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 Dictionary entry overview: What does thymidine mean? 

• THYMIDINE (noun)
  The noun THYMIDINE has 1 sense:

1. a nucleoside component of DNA; composed of thymine and deoxyribose

  Familiarity information: THYMIDINE used as a noun is very rare.

 Dictionary entry details 

• THYMIDINE (noun)

Sense 1

Meaning:

A nucleoside component of DNA; composed of thymine and deoxyribose

Classified under:

Nouns denoting substances

Synonyms:

deoxythymidine; thymidine

Hypernyms ("thymidine" is a kind of...):

nucleoside (a glycoside formed by partial hydrolysis of a nucleic acid)

 Context examples 

A halogenated thymidine analogue with potential antineoplastic and radiosensitizing activities.

(Broxuridine, NCI Thesaurus)

Edoxudine is activated by viral thymidine kinase to the 5'-monophosphate which is further phosphorylated by cellular enzymes to the 5'-triphosphate, a competitive inhibitor of the viral-coded DNA polymerase.

(Edoxudine, NCI Thesaurus)

A radioconjugate consisting of a thymidine analogue radiolabeled with fluorine F 18, a positron emitting isotope.

(Fluorothymidine F-18, NCI Thesaurus)

Omaciclovir is selectively phosphorylated by viral thymidine kinase to its monophosphate form and is further modified to a triphosphate, which is an inhibitor of VZV DNA polymerase.

(Omaciclovir, NCI Thesaurus)

A thymidine kinase-deleted vaccinia virus expressing human GM-CSF (hGM-CSF) with oncolytic activity.

(Pexastimogene-devacirepvec, NCI Thesaurus)

Acyclovir is further converted to cyclovir triphosphate by viral thymidine kinase and competitively inhibits viral DNA polymerase by incorporating into the growing viral DNA chain and terminating further polymerization.

(Desciclovir, NCI Thesaurus)

UL39 is replaced by the rat CYP2B1 gene, encoding a cytochrome P450 enzyme that activates oxazaphosphorines. rRp450 also expresses viral thymidine kinase, which activates the cancer prodrug ganciclovir.

(Oncolytic HSV-1 rRp450, NCI Thesaurus)

After conversion in vivo to the active metabolite acyclovir triphosphate by viral thymidine kinase, acyclovir competitively inhibits viral DNA polymerase by incorporating into the growing viral DNA chain and terminating further polymerization.

(Acyclovir, NCI Thesaurus)

The system detects pairs of gamma rays emitted indirectly by a positron-emitting radionuclide (tracer), which is introduced into the body on the biologically active molecule fluoro-L-thymidine (FLT).

(FLT-Positron Emission Tomography, NCI Thesaurus)

Lymphocytes from incompatible individuals will stimulate each other to proliferate significantly (usually measured by tritiated thymidine uptake) whereas those from compatible individuals will not.

(Mixed Lymphocyte Reaction Test, NCI Thesaurus)