THROMBOPLASTIN

Pronunciation (US):

(GB):

 Dictionary entry overview: What does thromboplastin mean? 

• THROMBOPLASTIN (noun)
  The noun THROMBOPLASTIN has 1 sense:

1. an enzyme liberated from blood platelets that converts prothrombin into thrombin as blood starts to clot

  Familiarity information: THROMBOPLASTIN used as a noun is very rare.

 Dictionary entry details 

• THROMBOPLASTIN (noun)

Sense 1

Meaning:

An enzyme liberated from blood platelets that converts prothrombin into thrombin as blood starts to clot

Classified under:

Nouns denoting substances

Synonyms:

factor III; thrombokinase; thromboplastin

Hypernyms ("thromboplastin" is a kind of...):

clotting factor; coagulation factor (any of the factors in the blood whose actions are essential for blood coagulation)

 Context examples 

The damaged tissue releases tissue thromboplastin also known as tissue factor (TF).

(Extrinsic Prothrombin Activation Pathway, NCI Thesaurus/BIOCARTA)

The determination of the ratio of a subject's partial thromboplastin time to a standard or control partial thromboplastin time.

(Activated PTT/Standard Ratio Measurement, NCI Thesaurus)

Lepirudin directly binds to and inactivates thrombin, producing dose-dependent increases in the activated partial thromboplastin time (aPTT) and prothrombin time (PT).

(Lepirudin, NCI Thesaurus)

A rare autosomal recessive inherited disorder characterized by prolonged partial thromboplastin time and absence of bleeding diathesis.

(High Molecular Weight Kininogen Deficiency, NCI Thesaurus)

Human coagulation factor-III protein (295 aa, 33 kDa precursor) is encoded by the human coagulation factor III (thromboplastin, tissue factor) (F3) gene.

(Coagulation Factor III, NCI Thesaurus)

Presence of a lupus inhibitor is most often detected by prolongation of the activated partial thromboplastin time.

(Lab Lupus Inhibitor Test, NCI Thesaurus)

The anticoagulant blocks in vitro assembly of the prothrombinase complex, resulting in prolongation of in vitro clotting assays such as the activated partial thromboplastin time, the russell viper venom time, and others.

(Lupus Anticoagulant Antibody, NCI Thesaurus)

Heat- and storage-stable plasma protein that is activated by tissue thromboplastin to form factor VIIa in the extrinsic pathway of blood coagulation.

(Coagulation Factor VII, NLM, Medical Subject Headings)

A ratio that represents the prothrombin time for a plasma specimen, divided by the result for a control plasma specimen, further standardized for the International Sensitivity Index of the tissue factor (thromboplastin) used in the test.

(International Normalized Ratio of Prothrombin Time, NCI Thesaurus/CDISC)

All results are standardized using the international sensitivity index (ISI) for the particular thromboplastin reagent and instrument combination utilized to perform the test; the ratio of a patient's clotting time to the lab's mean reference value is normalized against the ISI.

(International Normalized Ratio, NCI Thesaurus)