SUPERFAMILY

Pronunciation (US):

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IPA (US):

 Dictionary entry overview: What does superfamily mean? 

• SUPERFAMILY (noun)
  The noun SUPERFAMILY has 1 sense:

1. (biology) a taxonomic group ranking below an order but above a family

  Familiarity information: SUPERFAMILY used as a noun is very rare.

 Dictionary entry details 

• SUPERFAMILY (noun)

Sense 1

Meaning:

(biology) a taxonomic group ranking below an order but above a family

Classified under:

Nouns denoting groupings of people or objects

Hypernyms ("superfamily" is a kind of...):

taxon; taxonomic category; taxonomic group (animal or plant group having natural relations)

Domain category:

biological science; biology (the science that studies living organisms)

 Context examples 

Members of the G protein-coupled superfamily of receptors.

(Melatonin Receptor, NCI Thesaurus)

MSTN, a member of the transforming growth factor-beta (TGF-beta) superfamily, is a negative regulator of muscle growth and development.

(Anti-myostatin Monoclonal Antibody LY2495655, NCI Thesaurus)

CD30, a cell surface receptor and a member of the tumor necrosis factor (TNF) receptor superfamily, is overexpressed in hematologic malignancies; CD16A is specifically expressed on the surface of NK cells.

(Anti-CD30/CD16A Monoclonal Antibody AFM13, NCI Thesaurus)

DR5 is a cell surface receptor of the TNF-receptor superfamily and is expressed in a broad range of cancers.

(Apomab, NCI Thesaurus)

KIR, a member of the immunoglobulin superfamily, is expressed on the surface of NK cells.

(Anti-KIR Monoclonal Antibody IPH2102, NCI Thesaurus)

Her-2 (ErbB-2), a receptor tyrosine kinase (RTK) overexpressed by a variety of cancer cell types, belongs to the EGFR superfamily and plays key roles in both tumor cell proliferation and tumor angiogenesis.

(Anti-Her-2-CAR Retroviral Vector-Transduced Autologous Peripheral Blood Lymphocytes, NCI Thesaurus)

Metallothionein 3, encoded by the human MT3 gene, belongs to family 1 of the metallothionein superfamily.

(Metallothionein 3, NCI Thesaurus)

B7H1, a member of the B7 protein superfamily and a negative regulator of cytokine synthesis, is overexpressed on certain tumor cell types.

(Anti-B7H1 Monoclonal Antibody MEDI4736, NCI Thesaurus)

Transcription factors in the nuclear receptor superfamily for which a natural ligand has not been identified.

(Nuclear Orphan Receptor, NCI Thesaurus)

NGFR was the first member of the large superfamily of tumor necrosis factor receptors.

(Nerve Growth Factor Receptor, NCI Thesaurus)