STATIN

Pronunciation (US):

(GB):

 Dictionary entry overview: What does statin mean? 

• STATIN (noun)
  The noun STATIN has 1 sense:

1. a medicine that lowers blood cholesterol levels by inhibiting HMG-CoA reductase

  Familiarity information: STATIN used as a noun is very rare.

 Dictionary entry details 

• STATIN (noun)

Sense 1

Meaning:

A medicine that lowers blood cholesterol levels by inhibiting HMG-CoA reductase

Classified under:

Nouns denoting man-made objects

Synonyms:

lipid-lowering medication; lipid-lowering medicine; statin; statin drug

Hypernyms ("statin" is a kind of...):

medicament; medication; medicinal drug; medicine ((medicine) something that treats or prevents or alleviates the symptoms of disease)

Hyponyms (each of the following is a kind of "statin"):

atorvastatin; Lipitor (an oral drug (trade name Lipitor) that is effective in lowering triglycerides; potent in reducing LDL cholesterol because higher doses can be given)

Baycol; cerivastatin (an oral drug (trade name Baycol) to reduce blood cholesterol levels)

fluvastatin; Lescol (least expensive statin drug (trade name Lescol); usually taken orally at bedtime)

lovastatin; Mevacor (an oral drug (trade name Mevacor) to reduce blood cholesterol levels; used when dietary changes have proved inadequate)

Pravachol; pravastatin (an oral drug (trade name Pravachol) administered to reduce blood cholesterol levels; recommended after nonfatal heart attacks)

simvastatin; Zocor (an oral lipid-lowering medicine (trade name Zocor) administered to reduce blood cholesterol levels; recommended after heart attacks)

 Context examples 

Statins inhibit a key enzyme that helps make cholesterol.

(HMG-CoA reductase inhibitor, NCI Dictionary)

A novel statin that induces plaque regression and elevates HDL-cholesterol levels.

(Pitavastatin, NCI Thesaurus)

Mevastatin was the first statin to enter clinical trials.

(Mevastatin, NCI Thesaurus)

The statins are drugs commonly used to block cholesterol production and increase the expression of the LDL receptor by the liver, removing LDL from circulation.

(LDL Pathway, NCI Thesaurus/BIOCARTA)

In studies, its lipid-lowering effects were of a magnitude similar to that of the statins, but unlike statins, it had the ability to lower Lp(a), a risk factor in atherosclerosis.

(Lifibrol, NCI Thesaurus)

Older age, male gender, cirrhosis and diabetes also were independently associated with an increased risk, but nucleos(t)ide analogue or statin use was associated with a decreased risk.

(An Aspirin A Day Keep Liver Cancer Away, The Titi Tudorancea Bulletin)

Hydroxymethylglutaryl-coenzyme A reductase inhibitor drugs are called statins.

(hydroxymethylglutaryl-coenzyme A reductase inhibitor, NCI Dictionary)

It is a type of HMG-CoA reductase inhibitor and a type of statin.

(Atorvastatin, NCI Dictionary)

The new study sheds some light on the positive side effect of statin drugs lowering cancer risk.

(Researchers Zero-In on Cholesterol's Role in Cells, The Titi Tudorancea Bulletin)

But valve cells are quite unique and distinct from the smooth muscle cells in our blood vessels, which explains why some treatments for atherosclerosis, such as statins, don't work for CAVD.

(New Hope for Stopping An Understudied Heart Disease in Its Tracks, The Titi Tudorancea Bulletin)