SNP

Pronunciation (US):

(GB):

 Dictionary entry overview: What does SNP mean? 

• SNP (noun)
  The noun SNP has 1 sense:

1. (genetics) genetic variation in a DNA sequence that occurs when a single nucleotide in a genome is altered; SNPs are usually considered to be point mutations that have been evolutionarily successful enough to recur in a significant proportion of the population of a species

  Familiarity information: SNP used as a noun is very rare.

 Dictionary entry details 

• SNP (noun)

Sense 1

Meaning:

(genetics) genetic variation in a DNA sequence that occurs when a single nucleotide in a genome is altered; SNPs are usually considered to be point mutations that have been evolutionarily successful enough to recur in a significant proportion of the population of a species

Classified under:

Nouns denoting natural phenomena

Synonyms:

single nucleotide polymorphism; SNP

Hypernyms ("SNP" is a kind of...):

polymorphism ((genetics) the genetic variation within a population that natural selection can operate on)

Domain category:

genetic science; genetics (the branch of biology that studies heredity and variation in organisms)

 Context examples 

The CYP2C8*2 allele exhibits a clinically-relevant SNP (c.805A>T) in exon 5 that results in an I269F coding change.

(CYP2C8*2 Allele, NCI Thesaurus)

The CYP2C8*3 allele exhibits clinically-relevant SNPs (c.416G>A, c.1196A>G) in exons 3 and 8 that result in coding changes (R139K, K399R).

(CYP2C8*3 Allele, NCI Thesaurus)

The CYP2C8*4 allele exhibits a SNP (c.792C>G) in exon 5 that results in an I264M coding change.

(CYP2C8*4 Allele, NCI Thesaurus)

The CYP2C19*9 allele exhibits a clinically-relevant SNP (c.431G>A) in exon 3 that results in a R144H coding change.

(CYP2C19*9 Allele, NCI Thesaurus)

The CYP2C19*6 allele exhibits a clinically-relevant SNP (c.395G>A) in exon 3 that results in a R132Q coding change.

(CYP2C19*6 Allele, NCI Thesaurus)

The CYP2C19*4 allele exhibits a clinically-relevant SNP (c.1A>G) in the initiation codon that prevents translation of a protein product.

(CYP2C19*4 Allele, NCI Thesaurus)

The CYP2C19*5 allele exhibits a clinically-relevant SNP (c.1297C>T) in exon 9 that results in a R433W coding change in the heme-binding region of the protein.

(CYP2C19*5 Allele, NCI Thesaurus)

The CYP2C8*6 allele exhibits a SNP (c.511G>A) in exon 4 that results in a G171S coding change.

(CYP2C8*6 Allele, NCI Thesaurus)

The CYP2C8*7 allele exhibits a clinically-relevant SNP (c.556C>T) in exon 4 that results in a R186X coding change.

(CYP2C8*7 Allele, NCI Thesaurus)

The CYP2C9*18 allele exhibits a clinically-relevant SNP (c.1190A>C) in exon 8 that results in a D397A coding change.

(CYP2C9*18 Allele, NCI Thesaurus)