SINGLE NUCLEOTIDE POLYMORPHISM

Pronunciation (US):

(GB):

 Dictionary entry overview: What does single nucleotide polymorphism mean? 

• SINGLE NUCLEOTIDE POLYMORPHISM (noun)
  The noun SINGLE NUCLEOTIDE POLYMORPHISM has 1 sense:

1. (genetics) genetic variation in a DNA sequence that occurs when a single nucleotide in a genome is altered; SNPs are usually considered to be point mutations that have been evolutionarily successful enough to recur in a significant proportion of the population of a species

  Familiarity information: SINGLE NUCLEOTIDE POLYMORPHISM used as a noun is very rare.

 Dictionary entry details 

• SINGLE NUCLEOTIDE POLYMORPHISM (noun)

Sense 1

Meaning:

(genetics) genetic variation in a DNA sequence that occurs when a single nucleotide in a genome is altered; SNPs are usually considered to be point mutations that have been evolutionarily successful enough to recur in a significant proportion of the population of a species

Classified under:

Nouns denoting natural phenomena

Synonyms:

single nucleotide polymorphism; SNP

Hypernyms ("single nucleotide polymorphism" is a kind of...):

polymorphism ((genetics) the genetic variation within a population that natural selection can operate on)

Domain category:

genetic science; genetics (the branch of biology that studies heredity and variation in organisms)

 Context examples 

In this study, 74 single nucleotide polymorphisms (SNPs) were identified.

(Researchers identify genetic links to educational attainment, NIH)

Resequencing is used to identify single nucleotide polymorphisms (SNPs).

(DNA Resequencing, NCI Thesaurus)

Single nucleotide polymorphisms in the gene may contribute to breast cancer susceptibility.

(COX11 wt Allele, NCI Thesaurus)

A heritable single nucleotide polymorphism located at the acceptor splice site in certain allelic variants of eukaryotic genes.

(Acceptor Splice Site SNP, NCI Thesaurus)

DNA characteristics include, but are not limited to: single nucleotide polymorphisms (SNPs); variability of short sequence repeats; DNA modification, e.g., methylation; insertions; deletions; copy number variation; cytogenetic rearrangements, e.g., translocations, duplications, deletions or inversions.

(Genomic Biomarker, NCI Thesaurus)

The variations that exist can be as small as a difference in a single DNA building block—called a single nucleotide polymorphism (SNP)—or as large as whole sections of the genome being copied or moved.

(Genetic Adaptations to Diet and Climate, NIH)