SICKLE CELL

Pronunciation (US):

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 Dictionary entry overview: What does sickle cell mean? 

• SICKLE CELL (noun)
  The noun SICKLE CELL has 1 sense:

1. an abnormal red blood cell that has a crescent shape and an abnormal form of hemoglobin

  Familiarity information: SICKLE CELL used as a noun is very rare.

 Dictionary entry details 

• SICKLE CELL (noun)

Sense 1

Meaning:

An abnormal red blood cell that has a crescent shape and an abnormal form of hemoglobin

Classified under:

Nouns denoting body parts

Hypernyms ("sickle cell" is a kind of...):

erythrocyte; RBC; red blood cell (a mature blood cell that contains hemoglobin to carry oxygen to the bodily tissues; a biconcave disc that has no nucleus)

 Context examples 

One of the sickle cell disorders characterized by the presence of both hemoglobin S and hemoglobin C. It is similar to, but less severe than sickle cell anemia.

(Hemoglobin SC Disease, NLM, Medical Subject Headings)

Patients present with the symptoms of sickle cell disease but the latter are less frequent and severe compared to sickle cell disease.

(Hemoglobin SC Disease, NCI Thesaurus)

Red blood cell transfusions are commonly given to critically ill children for conditions such as trauma, cancer chemotherapy, intraoperative bleeding, and chronic conditions such as sickle cell disease and thalassemia.

(Fresh red blood cell transfusions do not help critically ill children more than older cells, National Institutes of Health)

Alteration in the expression of this gene is associated with cholangiocarcinoma, acute myeloid leukemia and sickle cell disease.

(MIR320A wt Allele, NCI Thesaurus)

Sickle cell anemia is an example.

(Genetic Disorders, NIH: National Library of Medicine)

Despite the mix, sickle cell disease was reversed.

(Stem cell transplant reverses sickle cell disease in adults, NIH)

A variant in the hemoglobin gene, a gene known for its role in sickle cell anemia, is associated with greater amount of blood glucose attached to hemoglobin in African-Americans.

(Study of multiethnic genomes identifies 27 genetic variants associated with disease, National Institutes of Health)

The new approach can be useful to diagnose infectious disorders associated with anaemia (such as malaria) and to screen for genetic anaemias such as thalassemia and sickle cell disease.

(New approach promises better anaemia detection, SciDev.Net)

By preventing selectin-mediated cell adhesion in sickle cell anemia, this agent may inhibit red blood cell-white blood cell interactions, normalize blood flow and reduce inflammation and vascular occlusive pain.

(Pan-Selectin Antagonist GMI-1070, NCI Thesaurus)

This gene is involved in the regulation of gene expression and plays a role in the development of cholangiocarcinoma, acute myeloid leukemia and sickle cell disease.

(MIR320A Gene, NCI Thesaurus)