SELF-RENEWAL

Pronunciation (US):

(GB):

IPA (US):

 Dictionary entry overview: What does self-renewal mean? 

• SELF-RENEWAL (noun)
  The noun SELF-RENEWAL has 1 sense:

1. the act of renewing yourself (or itself)

  Familiarity information: SELF-RENEWAL used as a noun is very rare.

 Dictionary entry details 

• SELF-RENEWAL (noun)

Sense 1

Meaning:

The act of renewing yourself (or itself)

Classified under:

Nouns denoting acts or actions

Hypernyms ("self-renewal" is a kind of...):

renewal (the act of renewing)

 Context examples 

Blood-cell development progresses from a hematopoietic stem cell (HSC), which can undergo either self-renewal or differentiation into a multilineage committed progenitor cell: a common lymphoid progenitor (CLP) or a common myeloid progenitor (CMP).

(Hematopoietic Cell Lineage Pathway, NCI Thesaurus/KEGG)

The choice between self-renewal and differentiation creates a fine balance between maintaining a pool of satellite cells for future repairs and making muscle cells for current tissue repair.

(Controlling Muscle Repair, NIH)

Malignant hematopoietic cell originating in the clonal proliferation of myeloid or lymphoid precursor that undergoes an aberrant and poorly regulated process of organogenesis resulted in arrested maturation and cell capacity for unlimited self-renewal.

(Leukemic Cell, NCI Thesaurus)

NR acts on the brain by normalizing levels of nicotinamide adenine dinucleotide (NAD+), a metabolite vital to cellular energy, stem cell self-renewal, resistance to neuronal stress and DNA repair.

(Compound prevents neurological damage, shows cognitive benefits in mouse model of Alzheimer’s disease, National Institutes of Health)