SEGREGATION

Pronunciation (US):

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IPA (US):

 Dictionary entry overview: What does segregation mean? 

• SEGREGATION (noun)
  The noun SEGREGATION has 3 senses:

1. (genetics) the separation of paired alleles during meiosis so that members of each pair of alleles appear in different gametes

2. a social system that provides separate facilities for minority groups

3. the act of segregating or sequestering

  Familiarity information: SEGREGATION used as a noun is uncommon.

 Dictionary entry details 

• SEGREGATION (noun)

Sense 1

Meaning:

(genetics) the separation of paired alleles during meiosis so that members of each pair of alleles appear in different gametes

Classified under:

Nouns denoting natural processes

Hypernyms ("segregation" is a kind of...):

biological process; organic process (a process occurring in living organisms)

Domain category:

genetic science; genetics (the branch of biology that studies heredity and variation in organisms)

Holonyms ("segregation" is a part of...):

meiosis; miosis; reduction division ((genetics) cell division that produces reproductive cells in sexually reproducing organisms; the nucleus divides into four nuclei each containing half the chromosome number (leading to gametes in animals and spores in plants))

Sense 2

Meaning:

A social system that provides separate facilities for minority groups

Classified under:

Nouns denoting groupings of people or objects

Synonyms:

segregation; separatism

Hypernyms ("segregation" is a kind of...):

social organisation; social organization; social structure; social system; structure (the people in a society considered as a system organized by a characteristic pattern of relationships)

Hyponyms (each of the following is a kind of "segregation"):

racial segregation (segregation by race)

de facto segregation (segregation (especially in schools) that happens in fact although not required by law)

de jure segregation (segregation that is imposed by law)

purdah; sex segregation (the traditional Hindu or Muslim system of keeping women secluded)

white separatism (a social system in which white people live separately from members of other races)

Derivation:

segregate (separate by race or religion; practice a policy of racial segregation)

segregationist (someone who believes the racial groups should be kept apart)

Sense 3

Meaning:

The act of segregating or sequestering

Classified under:

Nouns denoting acts or actions

Synonyms:

segregation; sequestration

Context example:

sequestration of the jury

Hypernyms ("segregation" is a kind of...):

separation (the social act of separating or parting company)

Antonym:

integration (the action of incorporating a racial or religious group into a community)

Derivation:

segregate (separate or isolate (one thing) from another and place in a group apart from others)

segregate (divide from the main body or mass and collect)

segregationist (someone who believes the racial groups should be kept apart)

 Context examples 

During meiosis, a single round of DNA replication is followed by two rounds of chromosome segregation, called meiosis I and meiosis II.

(Oocyte Meiosis Pathway, NCI Thesaurus/KEGG)

This gene plays a role in both chromosome segregation and telomerase regulation.

(PINX1 Gene, NCI Thesaurus)

This allele, which encodes PIN2/TERF1-interacting telomerase inhibitor 1 protein, is involved in both the modulation of telomerase activity and chromosome segregation.

(PINX1 wt Allele, NCI Thesaurus)

This protein plays a role in cell cycle progression and is required for both kinetochore formation and chromosome segregation during mitosis.

(Centromere Protein F, NCI Thesaurus)

This allele, which encodes CENP-F kinetochore protein, plays a role in mitotic chromosomal segregation.

(CENPF wt Allele, NCI Thesaurus)

AZD4877 selectively inhibits microtubule motor protein KSP (also called kinesin-5 or Eg5), which is essential for the formation of bipolar spindles and the proper segregation of sister chromatids during mitosis.

(KSP Inhibitor AZD4877, NCI Thesaurus)

Agents that modulate the activity of kinesins, specifically those that produce inhibitory effects, interfere with mitotic spindle assembly, organization and eventually, chromosome alignment and segregation, thereby inducing mitotic arrest.

(Mitotic Kinesin Modulator, NCI Thesaurus)

Auora kinase inhibitor MLN8054 binds to and inhibits Aurora kinase A, resulting in disruption of the assembly of the mitotic spindle apparatus, disruption of chromosome segregation, and inhibition of cell proliferation.

(Aurora Kinase Inhibitor MLN8054, NCI Thesaurus)

It is the aggregated products of microtubules during mitosis where chromosomes line up prior to the segregation process.

(Microtubule Bundle, NCI Thesaurus)

The checkpoints help maintain the proper order and timing of cell transition events, especially important for DNA replication and chromosome segregation.

(Cell Cycle Checkpoint, NCI Thesaurus)