SCLEROSIS (scleroses)

Pronunciation (US):

(GB):

IPA (US):

Irregular inflected form: scleroses   

 Dictionary entry overview: What does sclerosis mean? 

• SCLEROSIS (noun)
  The noun SCLEROSIS has 1 sense:

1. any pathological hardening or thickening of tissue

  Familiarity information: SCLEROSIS used as a noun is very rare.

 Dictionary entry details 

• SCLEROSIS (noun)

Sense 1

Meaning:

Any pathological hardening or thickening of tissue

Classified under:

Nouns denoting stable states of affairs

Synonyms:

induration; sclerosis

Hypernyms ("sclerosis" is a kind of...):

pathology (any deviation from a healthy or normal condition)

Hyponyms (each of the following is a kind of "sclerosis"):

disseminated multiple sclerosis; disseminated sclerosis; MS; multiple sclerosis (a chronic progressive nervous disorder involving loss of myelin sheath around certain nerve fibers)

ALS; amyotrophic lateral sclerosis; Lou Gehrig's disease (thickening of tissue in the motor tracts of the lateral columns and anterior horns of the spinal cord; results in progressive muscle atrophy that starts in the limbs)

arteriolosclerosis (sclerosis of the arterioles)

arterial sclerosis; arteriosclerosis; coronary-artery disease; hardening of the arteries; induration of the arteries (sclerosis of the arterial walls)

osteosclerosis (abnormal hardening or eburnation of bone)

Derivation:

sclerotic (relating to or having sclerosis; hardened)

 Context examples 

Nodular sclerosis Hodgkin lymphoma occurring in childhood.

(Childhood Nodular Sclerosis Classical Hodgkin Lymphoma, NCI Thesaurus)

A neoplasm with perivascular epithelioid cell differentiation often associated with tuberous sclerosis.

(Angiomyolipoma, NCI Thesaurus)

Multiple sclerosis affects women more than men.

(Multiple Sclerosis, NIH: National Institute of Neurological Disorders and Stroke)

It may be an isolated lesion or a component of one of a number of inherited disorders, such as tuberous sclerosis.

(Connective Tissue Nevus, NCI Thesaurus)

It may be caused by infection, drugs, toxins, and diseases of the immune system, such as multiple sclerosis.

(Optic neuritis, NCI Dictionary)

Causes include autoimmune disorders, infections, toxins, drugs, and multiple sclerosis.

(Optic neuritis, NCI Thesaurus)

Disease Steps in multiple sclerosis: A simple approach to evaluate disease progression.

(Patient Determined Disease Steps Questionnaire, NCI Thesaurus/CDISC)

Among people with early-stage multiple sclerosis (MS), those with higher blood levels of vitamin D had better outcomes during 5 years of follow-up.

(Vitamin D Levels Predict Multiple Sclerosis Progression, NIH)

Two drugs already on the market — an antifungal and a steroid — may potentially take on new roles as treatments for multiple sclerosis.

(Drugs that activate brain stem cells may reverse multiple sclerosis, NIH)

Disease steps in multiple sclerosis: a simple approach to evaluate disease progression.

(Disease Steps Questionnaire, NCI Thesaurus/CDISC)