SCLERODERMA

Pronunciation (US):

(GB):

IPA (US):

 Dictionary entry overview: What does Scleroderma mean? 

• SCLERODERMA (noun)
  The noun SCLERODERMA has 2 senses:

1. an autoimmune disease that affects the blood vessels and connective tissue; fibrous connective tissue is deposited in the skin

2. genus of poisonous fungi having hard-skinned fruiting bodies: false truffles

  Familiarity information: SCLERODERMA used as a noun is rare.

 Dictionary entry details 

• SCLERODERMA (noun)

Sense 1

Meaning:

An autoimmune disease that affects the blood vessels and connective tissue; fibrous connective tissue is deposited in the skin

Classified under:

Nouns denoting stable states of affairs

Synonyms:

dermatosclerosis; scleroderma

Hypernyms ("scleroderma" is a kind of...):

autoimmune disease; autoimmune disorder (any of a large group of diseases characterized by abnormal functioning of the immune system that causes your immune system to produce antibodies against your own tissues)

Hyponyms (each of the following is a kind of "scleroderma"):

morphea (localized scleroderma)

Sense 2

Meaning:

Genus of poisonous fungi having hard-skinned fruiting bodies: false truffles

Classified under:

Nouns denoting plants

Synonyms:

genus Scleroderma; Scleroderma

Hypernyms ("Scleroderma" is a kind of...):

fungus genus (includes lichen genera)

Meronyms (members of "Scleroderma"):

earthball; false truffle; hard-skinned puffball; puffball (any of various fungi of the genus Scleroderma having hard-skinned subterranean fruiting bodies resembling truffles)

Scleroderma aurantium; Scleroderma citrinum (an earthball fungus that is a dingy brownish yellow and a dark purplish interior; the peridium is covered with a pattern of small warts)

Scleroderma flavidium; star earthball (an earthball with a smooth upper surface that is at first buried in sand; the top of the fruiting body opens up to form segments like the ray of an umbel)

Scleroderma bovista; smooth earthball (an earthball with a peridium that is firm dry and smooth when young but developing cracks when mature; pale orange-yellow when young and reddish brown at maturity)

Holonyms ("Scleroderma" is a member of...):

family Sclerodermataceae; Sclerodermataceae (a family of fungi or order Sclerodermatales with a single-layered peridium; includes earthballs)

 Context examples 

An individual can have a combination of localized scleroderma types.

(Localized Scleroderma, NCI Thesaurus)

Still others, like scleroderma, have no known cause.

(Connective Tissue Disorders, NIH)

An autoimmune overlap syndrome characterized by the presence of symptoms of systemic lupus erythematosus, systemic scleroderma, and polymyositis.

(Mixed Connective Tissue Disease, NCI Thesaurus)

It is associated with portal hypertension, scleroderma, and chronic renal failure.

(Gastric Antral Vascular Ectasia, NCI Thesaurus)

It also may be associated with Lyme disease, Wegener's granulomatosis, Sjogren syndrome, cryoglobulinemia, hypereosinophilia, temporal arteritis, scleroderma, sarcoidosis, leprosy, acute viral hepatitis A, and acquired immunodeficiency syndrome.

(Mononeuritis Multiplex, NCI Thesaurus)

Pathologic Ab-Ig Proteins are immunoglobulin-related (IgA, IgD, IgE, IgG, IgM antibody) glycoproteins characteristically found in patients with multiple myeloma, infectious diseases, rheumatoid arthritis and other connective tissue diseases, or systemic autoimmune diseases including systemic lupus erythematosus, Sjogren's syndrome, scleroderma, polymyositis, and mixed connective tissue disease.

(Pathologic Ab-Ig Protein, NCI Thesaurus)

The shape, depth and location of the affected area is used to classify one of the four types of local scleroderma.

(Localized Scleroderma, NCI Thesaurus)

Localized scleroderma typically affects the skin, with formation of patches or lines of thick and unyielding tissue; there can be muscle and underlying tissue involvement as well as occasional joint complications.

(Localized Scleroderma, NCI Thesaurus)