SCHIZOPHRENIA

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 Dictionary entry overview: What does schizophrenia mean? 

• SCHIZOPHRENIA (noun)
  The noun SCHIZOPHRENIA has 1 sense:

1. any of several psychotic disorders characterized by distortions of reality and disturbances of thought and language and withdrawal from social contact

  Familiarity information: SCHIZOPHRENIA used as a noun is very rare.

 Dictionary entry details 

• SCHIZOPHRENIA (noun)

Sense 1

Meaning:

Any of several psychotic disorders characterized by distortions of reality and disturbances of thought and language and withdrawal from social contact

Classified under:

Nouns denoting stable states of affairs

Synonyms:

dementia praecox; schizophrenia; schizophrenic disorder; schizophrenic psychosis

Hypernyms ("schizophrenia" is a kind of...):

psychosis (any severe mental disorder in which contact with reality is lost or highly distorted)

Hyponyms (each of the following is a kind of "schizophrenia"):

borderline schizophrenia; latent schizophrenia (schizophrenia characterized by mild symptoms or by some preexisting tendency to schizophrenia)

catatonia; catatonic schizophrenia; catatonic type schizophrenia (a form of schizophrenia characterized by a tendency to remain in a fixed stuporous state for long periods; the catatonia may give way to short periods of extreme excitement)

disorganized schizophrenia; disorganized type schizophrenia; hebephrenia; hebephrenic schizophrenia (a form of schizophrenia characterized by severe disintegration of personality including erratic speech and childish mannerisms and bizarre behavior; usually becomes evident during puberty; the most common diagnostic category in mental institutions)

paranoic type schizophrenia; paranoid schizophrenia; paraphrenia; paraphrenic schizophrenia (a form of schizophrenia characterized by delusions (of persecution or grandeur or jealousy); symptoms may include anger and anxiety and aloofness and doubts about gender identity; unlike other types of schizophrenia the patients are usually presentable and (if delusions are not acted on) may function in an apparently normal manner)

acute schizophrenic episode; reactive schizophrenia (schizophrenia of abrupt onset and relatively short duration (a few weeks or months))

Derivation:

schizophrenic (suffering from some form of schizophrenia)

schizophrenic (of or relating to or characteristic of schizophrenia)

 Context examples 

Genetic copy number variation is associated with schizophrenia.

(MYT1L wt Allele, NCI Thesaurus)

The human form of this gene variant, Met66BDNF, leads to a reduction in the normal function of BDNF in the brain and is associated with several psychiatric disorders, including schizophrenia and depression.

(New study identifies gene variant linked to compulsive drinking, NIH)

Mutations in the gene may be associated with autism and copy number variation has been observed in patients with schizophrenia.

(NRXN1 wt Allele, NCI Thesaurus)

In total, their analyses included nearly 37,000 people with schizophrenia and a control group of more than 113,000 people who did not have the condition—the largest GWAS to date of a psychiatric disorder.

(Over 100 Genetic Sites Tied to Schizophrenia, NIH)

Problems with glutamate receptor function are thought to be involved in many disorders, including autism, schizophrenia, depression, Parkinson’s disease, and some types of cancer.

(Structural states of a brain receptor revealed, NIH)

Alteration in the expression of this gene is associated with development of breast cancer and schizophrenia.

(MIR206 wt Allele, NCI Thesaurus)

Deletion of this chromosomal region is associated with DiGeorge syndrome and loss of the gene may be associated with schizophrenia.

(DGCR8 wt Allele, NCI Thesaurus)

Copy number variation for the gene is associated with schizophrenia.

(CTNND2 wt Allele, NCI Thesaurus)

While it has no known role in oncogenesis, MIR198 plays a role in the development of schizophrenia.

(MIR198 Gene, NCI Thesaurus)

Alteration in the expression of this gene is associated with development of schizophrenia.

(MIR198 wt Allele, NCI Thesaurus)