English Dictionary |
RNASE
Pronunciation (US): | (GB): |
Dictionary entry overview: What does RNase mean?
• RNASE (noun)
The noun RNASE has 1 sense:
1. a transferase that catalyzes the hydrolysis of ribonucleic acid
Familiarity information: RNASE used as a noun is very rare.
Dictionary entry details
Sense 1
Meaning:
A transferase that catalyzes the hydrolysis of ribonucleic acid
Classified under:
Nouns denoting substances
Synonyms:
ribonuclease; ribonucleinase; RNase
Hypernyms ("RNase" is a kind of...):
transferase (any of various enzymes that move a chemical group from one compound to another compound)
Context examples
FEN 1 and RNase H1 remove the RNA from the Okazaki fragments and DNA ligase I joins the DNA.
(DNA Replication Pathway, NCI Thesaurus/KEGG)
Exonuclease 1, encoded by the EXO1 gene, is a 88-kD protein with 5-prime to 3-prime double strand DNA exonuclease activity as well as an RNase H activity.
(Exonuclease 1, NCI Thesaurus/LocusLink)
Upon intratumoral administration, one shRNA unit with a perfectly matched sequence renders the suppression of STMN1 mRNA translation (mRNA sequestration and cleavage-independent degradation) while the other unit with an imperfectly matched sequence renders STMN1 mRNA degradation via RNase H-like cleavage (cleavage-dependent mRNA silencing).
(pbi-shRNA STMN1 Lipoplex, NCI Thesaurus)
Normally, during replication of the lagging-strand DNA template, an RNA primer is removed either by an RNase H or by the 5 to 3 exonuclease activity of DNA pol I, and the DNA ligase joins the Okazaki fragments.
(DNA Replication Pathway, NCI Thesaurus/KEGG)
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