RICIN

Pronunciation (US):

(GB):

 Dictionary entry overview: What does ricin mean? 

• RICIN (noun)
  The noun RICIN has 1 sense:

1. a toxic protein extracted from castor beans; used as a chemical reagent; can be used as a bioweapon

  Familiarity information: RICIN used as a noun is very rare.

 Dictionary entry details 

• RICIN (noun)

Sense 1

Meaning:

A toxic protein extracted from castor beans; used as a chemical reagent; can be used as a bioweapon

Classified under:

Nouns denoting substances

Synonyms:

ricin; ricin toxin

Context example:

one milligram of ricin can kill an adult

Hypernyms ("ricin" is a kind of...):

albumen; albumin (a simple water-soluble protein found in many animal tissues and liquids)

toxin (a poisonous substance produced during the metabolism and growth of certain microorganisms and some higher plant and animal species)

 Context examples 

This immunotoxin was conjugated through SMPT linker, which confers a slower breakdown of the toxin, and limits specific cytotoxicity of ricin toxin to CD22-positive malignant cells.

(IgG-RFB4-SMPT-dgA Immunotoxin, NCI Thesaurus)

A human antibody which recognizes ricin epitopes.

(Human Anti-Ricin Antibody, NCI Thesaurus)

The ricin A chain component binds to B-cells and disrupts ribosomal activity and protein synthesis and induces cell cycle arrest.

(Monoclonal Antibody HD37-SMPT-dgA Immunotoxin, NCI Thesaurus)

This agent limits specific cytotoxicity of ricin toxin to CD22-positive malignant cells.

(Monoclonal Antibody Mono-dgA-RFB4, NCI Thesaurus)

The ricin component binds to cells and disrupts ribosomal activity and protein synthesis and induces cell cycle arrest.

(Murine MCA Ricin Conjugate, NCI Thesaurus)

An immunotoxin of monoclonal antibody (MoAb) RFB4 covalently linked to two deglycosylated ricin toxin A-chain (Di-dgA).

(Di-dgA-RFB4 Immunotoxin, NCI Thesaurus)

Monoclonal antibody K4-2C10 conjugated with deglycosylated ricin A chain.

(Anti-Endoglin Immunotoxin, NCI Thesaurus)

Both anti-CD19 IgG monoclonal antibody HD37 and anti-CD22 IgG monoclonal antibody RFB4 are attached to a single deglycosylated ricin A chain (dgA) via N-succinimidyl-oxycarbonyl-alpha-methyl-alpha-(2-pyridyldithio) toluene (SMPT) linker.

(Deglycosylated Ricin A Chain-Conjugated Anti-CD19/Anti-CD22 Immunotoxins, NCI Thesaurus)

A synthetic immunotoxin consisting of the murine monoclonal antibody N901 conjugated with toxin-blocked ricin (BR).

(Monoclonal Antibody N901-bR, NCI Thesaurus)

An immunotoxin comprised of an anti-B4 (anti-CD19) murine monoclonal antibody linked to the modified plant-derived toxin blocked ricin.

(Anti-B4 Blocked Ricin Immunotoxin, NCI Thesaurus)