REPRESSOR

Pronunciation (US):

(GB):

 Dictionary entry overview: What does repressor mean? 

• REPRESSOR (noun)
  The noun REPRESSOR has 1 sense:

1. an agent that represses

  Familiarity information: REPRESSOR used as a noun is very rare.

 Dictionary entry details 

• REPRESSOR (noun)

Sense 1

Meaning:

An agent that represses

Classified under:

Nouns denoting natural objects (not man-made)

Synonyms:

represser; repressor

Hypernyms ("repressor" is a kind of...):

agent (an active and efficient cause; capable of producing a certain effect)

 Context examples 

This gene plays a role both as an activator and repressor of transcription.

(MYBBP1A Gene, NCI Thesaurus)

MAD-MAX complexes repress transcription through recruitment of SIN3 co-repressor.

(mSin3, NCI Thesaurus)

By binding COUP-TF repressor and decreasing NF-kB Class I enhancer binding, E1A can repress MHC Class I gene transcription and allow tumor cells to avoid lysis by cytotoxic T lymphocytes.

(Oncogene E1A, NCI Thesaurus)

Their results suggest a novel mechanism of transcriptional control wherein ERR-a can function as a specific molecular repressor of PGC-1a.

(PGC1a Regulation Pathway, NCI Thesaurus/BIOCARTA)

Wnt activation also changes Pitx2 from a repressor to an activator by causing transcriptional corepressors like histone deacetylase 1 (HDAC1) bound to Pitx2 to be exchanged for coactivators.

(Pitx2 Transcription Regulation Pathway, NCI Thesaurus/BIOCARTA)

They include both transcriptional activators and repressors, and some are involved in myelopoiesis.

(CCAAT Enhancer Binding Protein, NCI Thesaurus)

This allele, which encodes transcriptional repressor CTCFL protein, is involved in both gene regulation and X-chromosome inactivation.

(CTCFL wt Allele, NCI Thesaurus)

Ubiquitous nuclear and cytoplasmic RNA Binding Protein EWS belongs to the TET family of RNP proteins, contains an RNA recognition motif and a RANBP2-type zinc finger, and may function as a repressor.

(Ewing Sarcoma Breakpoint Region 1 Protein, NCI Thesaurus)

During G1 phase, the Rb-HDAC repressor complex binds to the E2F-DP1 transcription factors, inhibiting downstream transcription.

(G1/S Checkpoint Pathway, NCI Thesaurus/BIOCARTA)

The NICD translocates to the nucleus, where it forms a complex with the DNA binding protein CSL, displacing a histone deacetylase (HDAc)-co-repressor (CoR) complex from CSL.

(Notch Signaling Pathway, NCI Thesaurus/KEGG)