RANDOMIZATION

Pronunciation (US):

(GB):

 Dictionary entry overview: What does randomization mean? 

• RANDOMIZATION (noun)
  The noun RANDOMIZATION has 1 sense:

1. a deliberately haphazard arrangement of observations so as to simulate chance

  Familiarity information: RANDOMIZATION used as a noun is very rare.

 Dictionary entry details 

• RANDOMIZATION (noun)

Sense 1

Meaning:

A deliberately haphazard arrangement of observations so as to simulate chance

Classified under:

Nouns denoting acts or actions

Synonyms:

randomisation; randomization

Hypernyms ("randomization" is a kind of...):

organisation; organization (the activity or result of distributing or disposing persons or things properly or methodically)

Derivation:

randomize (arrange in random order)

 Context examples 

In AdministrativeActivity, the categoryCode may = "Disposition" (off study, epoch completion), "Milestone" (informed consent, enrollment, registry, randomization) or "Other" (unblinding) activities.

(Defined Activity Category Code, NCI Thesaurus/BRIDG)

NOTE(S): A randomization book is a predefined set of assignments to portions of a study based on criteria, such as stratum group for example, that ensures a desired distribution of subjects across those portions of the study.

(Planned Randomization Book Allocation, NCI Thesaurus/BRIDG)

An activity defined at a global library level that identifies pre-treatment factors by which study subjects are segregated to assure balance of these factors before randomization to a study arm or some smaller segment of a study.

(Defined Stratification Criterion, NCI Thesaurus)

The Biostatistics Shared Resource works with Cancer Center investigators to define study/protocol objectives and endpoints, analyze pilot data, select an appropriate study design, blinding methods and randomization scheme, plan interim analyses, define an adequate sample size and accrual rate, develop and evaluate the statistical methods and analyse data, prepare statistical sections of the grant and protocol applications, analyze and design relational databases, forms and reports.

(Biostatistics Shared Resource, NCI Thesaurus)

This SDTM class captures planned protocol milestones such as randomization and study completion, and occurrences, conditions, or incidents independent of planned study evaluations occurring during the trial (e.g., adverse events) or prior to the trial (e.g., medical history).

(CDISC Events Class, NCI Thesaurus)

EXAMPLE(S): randomization, direct assignment based on eligibility criteria, etc. For escalating dose cohort studies, enroll subjects in successive arms, i.e., one arm is completely filled before any subjects are enrolled in the next arm.

(Defined Experimental Unit Allocation, NCI Thesaurus/BRIDG)

An activity that is intended to occur at some point in the course of a particular study and that is the assignment of an experimental unit to a portion of the study, such as an arm or a portion of an arm (when secondary allocations may occur) based on a randomization book.

(Planned Randomization Book Allocation, NCI Thesaurus)

An activity that is intended to occur at some point in the context of a particular study and that is the assignment of an experimental unit to a portion of the study, such as an arm or a portion of an arm (when secondary allocations may occur) based on a randomization book.

(Planned Randomization Book Allocation, NCI Thesaurus/BRIDG)