RAFTS

Pronunciation (US):

(GB):

IPA (US):

 Dictionary entry overview: What does rafts mean? 

• RAFTS (noun)
  The noun RAFTS has 1 sense:

1. a large number or amount

  Familiarity information: RAFTS used as a noun is very rare.

 Dictionary entry details 

• RAFTS (noun)

Sense 1

Meaning:

A large number or amount

Classified under:

Nouns denoting quantities and units of measure

Synonyms:

dozens; gobs; heaps; lashings; loads; lots; oodles; piles; rafts; scads; scores; slews; stacks; tons; wads

Context example:

she amassed stacks of newspapers

Hypernyms ("rafts" is a kind of...):

large indefinite amount; large indefinite quantity (an indefinite quantity that is above the average in size or magnitude)

 Context examples 

Lipid rafts, specialized microdomains of plasma membrane, are overexpressed in cancer cells compared to normal cells.

(Iodine I 124 Phospholipid Ether Analogue CLR1404, NCI Thesaurus)

Pre-TCR co-localizes with p56LCK kinase in membrane rafts resulting in phosphorylation of CD3-epsilon and ZAP70. p56LCK, in the TCR complex, activates DNA binding of STAT5A and STAT5B.

(Oncogene LCK, NCI Thesaurus)

The cholesterol gathers into "rafts," which were thought to serve as platforms from which other signaling molecules might operate.

(Researchers Zero-In on Cholesterol's Role in Cells, The Titi Tudorancea Bulletin)

Upon CBL phosphorylation, CAP/CBL dissociates from the receptor to complex with caveolar flotillin and localize to plasma membrane lipid rafts.

(CBL Protein, NCI Thesaurus)

During TCR engagement with MHC-associated antigen on host cell surfaces and synapse formation, CD3 activity leads to Tyr-phosphorylated CD3 subunits, Tyr phosphorylation of LAT colocalized in lipid rafts, and MAPK activation.

(CD3 Complex, NCI Thesaurus)

Encoded by human PAG Gene, ubiquitous 432-aa 47-kDa Phosphoprotein Associated with GEMs is a type III plasma transmembrane adaptor protein located predominantly in membrane rafts (GEMs), associated with FYN and CSK tyrosine kinase, and thought to be involved in T cell activation and immunoreceptor signal transduction.

(Phosphoprotein Associated with GEMs, NCI Thesaurus)

The activity of Csk also appears to depend on other factors such as CBP, which recruits Csk to the plasma membrane in lipid rafts where other signaling factors such the T cell receptor complex are localized.

(CSK Protein Kinase Activation Pathway, NCI Thesaurus/BIOCARTA)

Iodine I 124 phospholipid ether analogue CLR1404 is selectively taken up by tumor cells via membrane lipid rafts and accumulates in tumor cells.

(Iodine I 124 Phospholipid Ether Analogue CLR1404, NCI Thesaurus)