QUINONE

Pronunciation (US):

(GB):

 Dictionary entry overview: What does quinone mean? 

• QUINONE (noun)
  The noun QUINONE has 1 sense:

1. any of a class of aromatic yellow compounds including several that are biologically important as coenzymes or acceptors or vitamins; used in making dyes

  Familiarity information: QUINONE used as a noun is very rare.

 Dictionary entry details 

• QUINONE (noun)

Sense 1

Meaning:

Any of a class of aromatic yellow compounds including several that are biologically important as coenzymes or acceptors or vitamins; used in making dyes

Classified under:

Nouns denoting substances

Synonyms:

benzoquinone; quinone

Hypernyms ("quinone" is a kind of...):

chemical compound; compound ((chemistry) a substance formed by chemical union of two or more elements or ingredients in definite proportion by weight)

Hyponyms (each of the following is a kind of "quinone"):

coenzyme Q; ubiquinone (any of several quinones found in living cells and that function as coenzymes that transfer electrons from one molecule to another in cell respiration)

 Context examples 

Dihydroorotate dehydrogenase (quinone), mitochondrial (395 aa, ~43 kDa) is encoded by the human DHODH gene.

(Dihydroorotate Dehydrogenase (Quinone), Mitochondrial, NCI Thesaurus)

This allele, which encodes ribosyldihydronicotinamide dehydrogenase [quinone] protein, plays a role in both vitamin metabolism and detoxification.

(NQO2 wt Allele, NCI Thesaurus)

This gene is involved in the reduction of quinones.

(NQO2 Gene, NCI Thesaurus)

The alkylating group in carboquone becomes activated upon reduction of quinone to the hydroquinone form.

(Carboquone, NCI Thesaurus)

Bioactivation of aziridinylbenzoquinone RH1 occurs through the two-electron reduction of the quinone to the hydroquinone by the two-electron quinone reductase DT-diaphorase (DTD).

(Aziridinylbenzoquinone RH1, NCI Thesaurus)

This agent displays selectivity activity towards both hypoxic solid tumors, which exhibits higher expression of cytochrome P450 reductase, and well-oxygenated malignant cells that overexpress the bioreductive enzyme NQO1 (NAD(P)H: quinone oxidoreductase).

(Apaziquone, NCI Thesaurus)

This allele, which encodes NAD(P)H dehydrogenase [quinone] 1 protein, plays a role in the reduction of quinones to hydroquinones.

(NQO1 wt Allele, NCI Thesaurus)

The NQO1 *2 allele has a C609T substitution in the cDNA, which encodes NAD(P)H dehydrogenase [quinone] 1*2 protein that results in the amino acid change P187S.

(NQO1*2 Allele, NCI Thesaurus)

NAD(P)H dehydrogenase [quinone] 1 (274 aa, ~31 kDa) is encoded by the human NQO1 gene.

(NAD(P)H Dehydrogenase [Quinone] 1, NCI Thesaurus)

The Ah receptor/ARNT heterodimer binds to dioxin-responsive elements and alters expression of a number of genes including; CYP1A1, CYP1A2, CYP1B1, and NAD(P)H quinone oxidoreductase.

(AHR Signal Transduction Pathway, NCI Thesaurus/BIOCARTA)