PURKINJE

Pronunciation (US):

(GB):

• PURKINJE (noun)
  The noun PURKINJE has 1 sense:

1. Bohemian physiologist remembered for his discovery of Purkinje cells and the Purkinje network (1787-1869)

  Familiarity information: PURKINJE used as a noun is very rare.

• PURKINJE (noun)

Sense 1

Meaning:

Bohemian physiologist remembered for his discovery of Purkinje cells and the Purkinje network (1787-1869)

Classified under:

Nouns denoting people

Synonyms:

Jan Evangelista Purkinje; Johannes Evangelista Purkinje; Purkinje

Instance hypernyms:

physiologist (a biologist specializing in physiology)

 Context examples 

It consists of the granular layer, molecular layer, and Purkinje cell layer.

(Cortical Cell Layer of the Cerebellum, NCI Thesaurus)

Mexiletine exerts its antiarrhythmic effect by inhibiting the inward sodium current in cardiac cells, thereby reducing the rate of rise of the cardiac action potential (phase 0) and decreases automaticity in the Purkinje fibers.

(Mexiletine, NCI Thesaurus)

The agent decreases the flow of sodium ions into myocardial tissue, especially on the Purkinje network, during phase 0 of the action potential, thereby decreasing depolarization, automaticity and excitability.

(Lidocaine Hydrochloride, NCI Thesaurus)

As a class Ic antiarrhythmic that blocks sodium channels, flecainide depresses polarization phase 0 and decreases the induction velocity of the His-Purkinje system.

(Flecainide, NCI Thesaurus)

Cerebellar long-term depression (LTD), thought to be a molecular and cellular basis for cerebellar learning, is a process involving a decrease in the synaptic strength between parallel fiber (PF) and Purkinje cells (PCs) induced by the conjunctive activation of PFs and climbing fiber (CF).

(Long-Term Depression Pathway, NCI Thesaurus/KEGG)