PROTO-ONCOGENE

Pronunciation (US):

(GB):

IPA (US):

 Dictionary entry overview: What does proto-oncogene mean? 

• PROTO-ONCOGENE (noun)
  The noun PROTO-ONCOGENE has 1 sense:

1. a normal gene that has the potential to become an oncogene

  Familiarity information: PROTO-ONCOGENE used as a noun is very rare.

 Dictionary entry details 

• PROTO-ONCOGENE (noun)

Sense 1

Meaning:

A normal gene that has the potential to become an oncogene

Classified under:

Nouns denoting body parts

Hypernyms ("proto-oncogene" is a kind of...):

cistron; factor; gene ((genetics) a segment of DNA that is involved in producing a polypeptide chain; it can include regions preceding and following the coding DNA as well as introns between the exons; it is considered a unit of heredity)

 Context examples 

This allele, which encodes proto-oncogene protein c-fos, is involved in the regulation of transcription by RNA polymerase II.

(FOS wt Allele, NCI Thesaurus)

This allele, which encodes proto-oncogene FRAT1 protein, is involved in the promotion of Wnt protein mediated signal transduction.

(FRAT1 wt Allele, NCI Thesaurus)

This allele, which encodes proto-oncogene tyrosine-protein kinase Fyn protein, is involved in protocadherin signaling and regulation of T-cell signaling.

(FYN wt Allele, NCI Thesaurus)

Proto-oncogenes are ordinarilly involved in transduction of signals that regulate cell growth and differentiation.

(Oncogene Activation Process, NCI Thesaurus)

Fibroblast Growth Factor 6 is encoded by the HST2 proto-oncogene and belongs to the heparin-binding growth factor family.

(Fibroblast Growth Factor 6, NCI Thesaurus)

This allele, which encodes INT-2 proto-oncogene protein, plays a role in cellular growth and signal transduction.

(FGF3 wt Allele, NCI Thesaurus)

This allele, which encodes proto-oncogene tyrosine-protein kinase FGR protein, is involved in the regulation of outside-in signaling-dependent sustained neutrophil adhesion.

(FGR wt Allele, NCI Thesaurus)

Proto-oncogenes that code for G proteins.

(G Protein Gene, NCI Thesaurus)

The c-erbA proto-oncogene encodes the thyroid hormone receptors (RECEPTORS, THYROID HORMONE).

(Oncogene ERB A, NLM, Medical Subject Headings)

This allele, which encodes N-myc proto-oncogene protein, is involved in the modulation of transcription by RNA polymerase II.

(MYCN wt Allele, NCI Thesaurus)