PROTEOME

Pronunciation (US):

(GB):

 Dictionary entry overview: What does proteome mean? 

• PROTEOME (noun)
  The noun PROTEOME has 1 sense:

1. the full complement of proteins produced by a particular genome

  Familiarity information: PROTEOME used as a noun is very rare.

 Dictionary entry details 

• PROTEOME (noun)

Sense 1

Meaning:

The full complement of proteins produced by a particular genome

Classified under:

Nouns denoting substances

Hypernyms ("proteome" is a kind of...):

protein (any of a large group of nitrogenous organic compounds that are essential constituents of living cells; consist of polymers of amino acids; essential in the diet of animals for growth and for repair of tissues; can be obtained from meat and eggs and milk and legumes)

 Context examples 

Several projects are now underway to characterize the human proteome.

(Revealing the human proteome, NIH)

Provides a top level guide to the main databases that describe the proteomes of higher eukaryotic organisms.

(International Protein Index, NCI Thesaurus)

The study characterised the genetic underpinnings of the human plasma ‘proteome’, identifying nearly 2,000 genetic associations with almost 1,500 proteins.

(Scientists create ‘genetic atlas’ of proteins in human blood, University of Cambridge)

One difference between genome sequencing and so-called ‘proteomics’ – studying an individual’s proteins in depth – is that whereas the genome is fixed, the proteome changes over time.

(Study highlights potential for ‘liquid health check’ to predict disease risk, University of Cambridge)

The scientists found this shortening of lifespan to be consistent with the nature of the proteome collapse process.

(Study reveals how collapse of protein processes is driver of aging and death, National Science Foundation)

Researchers identified an almost complete set of proteins, a proteome, in the dental enamel of the rhino and the genetic information discovered is one million years older than the oldest DNA sequenced from a 700,000-year-old horse.

(‘Game-changing’ research could solve evolution mysteries, University of Cambridge)

However, scientific understanding of the proteome has lagged behind that of the genome, partly because of the proteome’s complexities.

(Revealing the human proteome, NIH)

Co-author Ken Dill of Stony Brook said that the research team developed a Proteome Collapse Model that explores a central question in biology: How does the folding health of a proteome, the entire complement of a cell's proteins, change with damage and age?

(Study reveals how collapse of protein processes is driver of aging and death, National Science Foundation)

The resulting draft human proteome map includes proteins encoded by more than 17,000 genes—about 84% of the total known protein-coding genes.

(Revealing the human proteome, NIH)

Researchers completed a draft map of the human proteome—the set of all proteins in the human body.

(Revealing the human proteome, NIH)