PROTEINASE

Pronunciation (US):

(GB):

 Dictionary entry overview: What does proteinase mean? 

• PROTEINASE (noun)
  The noun PROTEINASE has 1 sense:

1. any enzyme that catalyzes the splitting of proteins into smaller peptide fractions and amino acids by a process known as proteolysis

  Familiarity information: PROTEINASE used as a noun is very rare.

 Dictionary entry details 

• PROTEINASE (noun)

Sense 1

Meaning:

Any enzyme that catalyzes the splitting of proteins into smaller peptide fractions and amino acids by a process known as proteolysis

Classified under:

Nouns denoting substances

Synonyms:

peptidase; protease; proteinase; proteolytic enzyme

Hypernyms ("proteinase" is a kind of...):

enzyme (any of several complex proteins that are produced by cells and act as catalysts in specific biochemical reactions)

Hyponyms (each of the following is a kind of "proteinase"):

caspase (any of a group of proteases that mediate apoptosis)

ACE; angiotensin-converting enzyme; angiotensin converting enzyme (proteolytic enzyme that converts angiotensin I into angiotensin II)

plasminogen activator; urokinase (protease produced in the kidney that converts plasminogen to plasmin and so initiates fibrinolysis)

renin (a proteolytic enzyme secreted by the kidneys; catalyzes the formation of angiotensin and thus affects blood pressure)

 Context examples 

Cystatin Family Genes encode (Type 2) Cystatin proteins, secreted, tight, reversible, competitive inhibitors of cysteine proteinases that contain multiple cystatin-like sequences and have 2 intrachain disulfide bonds.

(Cystatin Family Gene, NCI Thesaurus)

Human serum-derived alpha-1 proteinase inhibitor (alpha-1-antitrypsin or AAT) with immunomodulating and anti-inflammatory activity.

(Alpha-1-Proteinase Inhibitor Human, NCI Thesaurus)

This protein is involved in the inhibition of cysteine proteinases.

(Cystatin-C, NCI Thesaurus)

Kringles are also present in coagulation-related and fibrinolytic proteins and other plasma proteinases.

(Kringle Domain, NLM, Medical Subject Headings)

This protein is involved in the regulation of serine proteinases, spermatogenesis and fusion of sperm with the plasma membrane of an egg.

(Plasma Serine Protease Inhibitor, NCI Thesaurus)

BBIC is made from soybeans, and is a type of serine proteinase inhibitor.

(Bowman-Birk inhibitor concentrate, NCI Dictionary)

These genes encode caspases, a family of intracellular cysteine proteinases involved in inflammation and apoptosis.

(Caspase Gene, NCI Thesaurus)

This protein is involved in the negative regulation of serine proteinase activity during blood coagulation.

(Antithrombin-III, NCI Thesaurus)

This protein is involved in the regulation of serine proteinase activity.

(Antileukoproteinase, NCI Thesaurus)

Poorly cleared by the lymphatic system, this formulation undergoes increased cleavage by tumor cell lysosomal proteinases, resulting in increased, sustained intracellular concentrations of free doxorubicin.

(Doxorubicin-HPMA Conjugate, NCI Thesaurus)