PROSTATE SPECIFIC ANTIGEN

Pronunciation (US):

(GB):

IPA (US):

 Dictionary entry overview: What does prostate specific antigen mean? 

• PROSTATE SPECIFIC ANTIGEN (noun)
  The noun PROSTATE SPECIFIC ANTIGEN has 1 sense:

1. a protein manufactured exclusively by the prostate gland; PSA is produced for the ejaculate where it liquifies the semen and allows sperm cells to swim freely; elevated levels of PSA in blood serum are associated with benign prostatic hyperplasia and prostate cancer

  Familiarity information: PROSTATE SPECIFIC ANTIGEN used as a noun is very rare.

 Dictionary entry details 

• PROSTATE SPECIFIC ANTIGEN (noun)

Sense 1

Meaning:

A protein manufactured exclusively by the prostate gland; PSA is produced for the ejaculate where it liquifies the semen and allows sperm cells to swim freely; elevated levels of PSA in blood serum are associated with benign prostatic hyperplasia and prostate cancer

Classified under:

Nouns denoting substances

Synonyms:

prostate specific antigen; PSA

Hypernyms ("prostate specific antigen" is a kind of...):

protein (any of a large group of nitrogenous organic compounds that are essential constituents of living cells; consist of polymers of amino acids; essential in the diet of animals for growth and for repair of tissues; can be obtained from meat and eggs and milk and legumes)

 Context examples 

A prostate cancer vaccine containing mRNAs encoding prostate specific antigen (PSA), prostate specific membrane antigen (PSMA), prostate stem cell antigen (PSCA) and six-transmembrane epithelial antigen of the prostate (STEAP), with potential antitumor activity.

(mRNA-Derived Prostate Cancer Vaccine CV9103, NCI Thesaurus)

A cancer vaccine consisting of a recombinant modified vaccinia Ankara (MVA) viral vector encoding genes for prostate specific antigen (PSA) and prostate acid phosphatase (PAP) with potential immunostimulatory and antineoplastic activities.

(MVA-PSA/PAP Prostate Cancer Vaccine, NCI Thesaurus)

In addition, MCP decreases prostate specific antigen (PSA) levels and may remove heavy metals.

(Modified Citrus Pectin Supplement, NCI Thesaurus)

In addition to sharing a number of common B and T cell determinants with Mycobacterium leprae and Mycobacterium tuberculosis, Mycobacterium w (Mw) also shares an immunogenic determinant with prostate specific antigen (PSA).

(Mycobacterium w, NCI Thesaurus)

A prostate cancer vaccine containing six messenger RNAs (mRNAs) encoding for antigens upregulated in prostate cancer, including mRNAs for prostate specific antigen (PSA), prostate specific membrane antigen (PSMA), prostatic acid phosphatase (PAP), and mucin 1 (MUC1), with potential antineoplastic and immunomodulating activities.

(mRNA-derived Prostate Cancer Vaccine CV9104, NCI Thesaurus)

Through a mechanism that is reported to be different from other approved AR antagonists, enzalutamide inhibits the activity of prostate cancer cell ARs, which may result in a reduction in prostate cancer cell proliferation and, correspondingly, a reduction in the serum prostate specific antigen (PSA) level.

(Enzalutamide, NCI Thesaurus)