PROLIFERATION

Pronunciation (US):

(GB):

IPA (US):

 Dictionary entry overview: What does proliferation mean? 

• PROLIFERATION (noun)
  The noun PROLIFERATION has 2 senses:

1. growth by the rapid multiplication of parts

2. a rapid increase in number (especially a rapid increase in the number of deadly weapons)

  Familiarity information: PROLIFERATION used as a noun is rare.

 Dictionary entry details 

• PROLIFERATION (noun)

Sense 1

Meaning:

Growth by the rapid multiplication of parts

Classified under:

Nouns denoting natural processes

Hypernyms ("proliferation" is a kind of...):

development; growing; growth; maturation; ontogenesis; ontogeny ((biology) the process of an individual organism growing organically; a purely biological unfolding of events involved in an organism changing gradually from a simple to a more complex level)

Derivation:

proliferate (cause to grow or increase rapidly)

proliferate (grow rapidly)

Sense 2

Meaning:

A rapid increase in number (especially a rapid increase in the number of deadly weapons)

Classified under:

Nouns denoting natural processes

Context example:

the proliferation of nuclear weapons

Hypernyms ("proliferation" is a kind of...):

growth; increase; increment (a process of becoming larger or longer or more numerous or more important)

Antonym:

non-proliferation; nonproliferation (the prevention of something increasing or spreading (especially the prevention of an increase in the number of countries possessing nuclear weapons))

Derivation:

proliferate (cause to grow or increase rapidly)

proliferate (grow rapidly)

 Context examples 

A low-grade malignant neoplasm composed of epithelial cells and a spindle cell osteo-fibrous proliferation.

(Adamantinoma, NCI Thesaurus/CDISC)

This may inhibit tumor cell proliferation in ER-positive tumor cells.

(Acolbifene hydrochloride, NCI Thesaurus)

The CTLs specifically kill tumor cells expressing the TAA, which results in a reduction of tumor cell proliferation.

(AAV-DC-CTL Tumor Cell Targeting Therapy, NCI Thesaurus)

This protein is involved in cell proliferation and tyrosine phosphorylation.

(Megakaryocyte-Associated Tyrosine-Protein Kinase, NCI Thesaurus)

This protein plays a role in the repression of melanoma cell proliferation.

(Melanoma-Derived Growth Regulatory Protein, NCI Thesaurus)

Metamelfalan causes crosslinking of DNA, thereby preventing DNA replication and eventually cellular proliferation.

(Metamelfalan, NCI Thesaurus)

This protein is involved in the negative regulation of transcription, cell proliferation and signaling.

(Menin, NCI Thesaurus)

Lactate is one of the fuels that supports growth, proliferation, and maybe even lung cancer metastases.

(Study Challenges Long-Standing Concept in Cancer Metabolism, The Titi Tudorancea Bulletin)

The expressed endostatin may inhibit endothelial cell proliferation and angiogenesis which may result in a reduction of tumor growth.

(Adenovirus Encoding Recombinant Human Endostatin, NCI Thesaurus)

The team also found that Stat3 inhibition promoted the proliferation of human muscle cells.

(Controlling Muscle Repair, NIH)