PROLIFERATE

Pronunciation (US):

(GB):

IPA (US):

 Dictionary entry overview: What does proliferate mean? 

• PROLIFERATE (verb)
  The verb PROLIFERATE has 2 senses:

1. grow rapidly

2. cause to grow or increase rapidly

  Familiarity information: PROLIFERATE used as a verb is rare.

 Dictionary entry details 

• PROLIFERATE (verb)

Present simple: I / you / we / they proliferate    ... he / she / it proliferates   
Past simple: proliferated   
Past participle: proliferated   
-ing form: proliferating   

Sense 1

Meaning:

Grow rapidly

Classified under:

Verbs of size, temperature change, intensifying, etc.

Context example:

Pizza parlors proliferate in this area

Hypernyms (to "proliferate" is one way to...):

grow (become larger, greater, or bigger; expand or gain)

Verb group:

proliferate (cause to grow or increase rapidly)

Sentence frame:

Something ----s

Derivation:

proliferation (growth by the rapid multiplication of parts)

proliferation (a rapid increase in number (especially a rapid increase in the number of deadly weapons))

Sense 2

Meaning:

Cause to grow or increase rapidly

Classified under:

Verbs of size, temperature change, intensifying, etc.

Context example:

We must not proliferate nuclear arms

Hypernyms (to "proliferate" is one way to...):

manifold; multiply (combine or increase by multiplication)

Verb group:

proliferate (grow rapidly)

Sentence frame:

Something ----s

Derivation:

proliferation (growth by the rapid multiplication of parts)

proliferation (a rapid increase in number (especially a rapid increase in the number of deadly weapons))

 Context examples 

This nuclear protein interacts with the proliferating cell nuclear antigen (PCNA), a component of DNA replication/repair complexes, and the cyclin dependent kinase inhibitor p21Cip1.

(Growth Arrest and DNA-Damage-Inducible, Alpha, NCI Thesaurus)

B cells that are activated by antigen binding and that interact with the T cell receptor through the B cell MHC II appear to become resistant to Fas-mediated apoptosis, survive and proliferate.

(Bystander B Cell Activation Pathway, NCI Thesaurus/BIOCARTA)

Having to do with the presence of dividing (proliferating) cells.

(Mitotic activity, NCI Dictionary)

Anguidine inhibits initiation of protein synthesis, resulting in the death of rapidly proliferating cells.

(Anguidine, NCI Thesaurus)

B cells are not activated by antigen on their own, but require interaction with helper CD4+ T cells to become activated and proliferate.

(Antigen Dependent B Cell Activation Pathway, NCI Thesaurus/BIOCARTA)

It is a general indication of how fast a tissue or cell sample is proliferating.

(Cell Cycle Kinetics, NCI Thesaurus)

Consequently, they are not exposed to radiation damage, which only affects proliferating cells.

(New Way Discovered for Protecting against High-Dose Radiation Damage, The Titi Tudorancea Bulletin)

Proliferating cells are mixed with other mucosal cells.

(Neuroendocrine Cell Hyperplasia of the Mouse Intestinal Tract, NCI Thesaurus/MMHCC)

It is composed of irregular proliferating nests and islands of epithelium, including solid and gland-like sebaceous elements, surrounded by lymphoid stroma.

(Parotid Gland Sebaceous Lymphadenoma, NCI Thesaurus)

This allele, which encodes proliferating cell nuclear antigen immunoprotein, is involved in the regulation of DNA processivity activities.

(PCNA wt Allele, NCI Thesaurus)