PREMENOPAUSAL

Pronunciation (US):

(GB):

 Dictionary entry overview: What does premenopausal mean? 

• PREMENOPAUSAL (adjective)
  The adjective PREMENOPAUSAL has 1 sense:

1. prior to menopause

  Familiarity information: PREMENOPAUSAL used as an adjective is very rare.

 Dictionary entry details 

• PREMENOPAUSAL (adjective)

Sense 1

Meaning:

Prior to menopause

Classified under:

Relational adjectives (pertainyms)

Pertainym:

menopause (the time in a woman's life in which the menstrual cycle ends)

 Context examples 

It is also being studied in the prevention of breast cancer in certain premenopausal women and in the prevention and treatment of other conditions.

(Evista, NCI Dictionary)

Elevated serum levels of insulin-like growth factor-1 (IGF-1) may identify premenopausal women who are likely to develop breast cancer before age 50.

(Insulin-Like Growth Factor 1, NCI Thesaurus)

Osteoporosis is classified as primary (Type 1, postmenopausal osteoporosis; Type 2, age-associated osteoporosis; and idiopathic, which can affect juveniles, premenopausal women, and middle-aged men) and secondary osteoporosis (which results from an identifiable cause of bone mass loss).

(Osteoporosis, NCI Thesaurus)

Aromatase, a cytochrome P-450 enzyme localized to the endoplasmic reticulum of the cell and found in many tissues including those of the premenopausal ovary, liver, and breast, catalyzes the aromatization of androstenedione and testosterone into estrone and estradiol, the final step in estrogen biosynthesis.

(Letrozole, NCI Thesaurus)

As a third-generation aromatase inhibitor, anastrozole selectively binds to and reversibly inhibits aromatase, a cytochrome P-450 enzyme complex found in many tissues including those of the premenopausal ovary, liver, and breast; aromatase catalyzes the aromatization of androstenedione and testosterone into estrone and estradiol, the final step in estrogen biosynthesis.

(Anastrozole, NCI Thesaurus)