POLYMYXIN

Pronunciation (US):

(GB):

 Dictionary entry overview: What does polymyxin mean? 

• POLYMYXIN (noun)
  The noun POLYMYXIN has 1 sense:

1. any of several toxic antibiotics obtained from a particular soil bacterium

  Familiarity information: POLYMYXIN used as a noun is very rare.

 Dictionary entry details 

• POLYMYXIN (noun)

Sense 1

Meaning:

Any of several toxic antibiotics obtained from a particular soil bacterium

Classified under:

Nouns denoting man-made objects

Hypernyms ("polymyxin" is a kind of...):

antibiotic; antibiotic drug (a chemical substance derivable from a mold or bacterium that can kill microorganisms and cure bacterial infections)

 Context examples 

The sodium salt of colistimethate, a broad-spectrum polymyxin antibiotic against most aerobic Gram-negative bacteria except Proteus bacteria.

(Colistimethate Sodium, NCI Thesaurus)

A broad-spectrum polymyxin antibiotic against most aerobic Gram-negative bacteria except Proteus bacteria.

(Colistimethate, NCI Thesaurus)

Any of the sterile, commercial combination preparations, by Pfizer, containing neomycin sulfate and polymyxin B sulfate, as the main active ingredients, for ophthalmic treatments.

(Neosporin Ophthalmic, NCI Thesaurus)

A commercial combination preparation containing the aminoglycoside antibiotic neomycin sulfate and the polypeptide antibiotic polymyxin B sulfate, by Pfizer, in a cream with topical antibacterial activity.

(Neosporin Cream, NCI Thesaurus)

Polymyxin B, neomycin and bacitracin zinc exert antibacterial effects through a cationic detergent-like action on cell membranes, inhibition of protein synthesis, and inhibition of peptidoglycan synthesis, respectively.

(Cortisporin Formulation, NCI Thesaurus)

This species is nonmotile, non-spore forming, indole positive, produces hydrogen sulfide, hydrolyzes esculin, but not starch, does not reduce nitrate, and is resistant to aminoglycosides and polymyxins.

(Bacteroides splanchnicus, NCI Thesaurus)

A combination preparation containing the polypeptide antibiotic polymyxin b, the aminoglycoside antibiotic neomycin, the glucocorticoid hydrocortisone and, in some formulations, the antibiotic bacitracin zinc with antibacterial and anti-inflammatory activities.

(Cortisporin Formulation, NCI Thesaurus)

Polymyxin B sulfate, a polypeptide produced by Bacillus polymyxa, binds to the negatively charged phospholipids in the cell membrane, thereby altering the permeability of the bacterial cytoplasmic membrane.

(Neosporin Ophthalmic, NCI Thesaurus)

Polymyxin B sulfate, a polypeptide produced by Bacillus polymyxa, binds to negatively charged phospholipids in the cell membrane, thereby altering the permeability of the bacterial cytoplasmic membrane.

(Neosporin Cream, NCI Thesaurus)