POLYMERASE

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 Dictionary entry overview: What does polymerase mean? 

• POLYMERASE (noun)
  The noun POLYMERASE has 1 sense:

1. an enzyme that catalyzes the formation of new DNA and RNA from an existing strand of DNA or RNA

  Familiarity information: POLYMERASE used as a noun is very rare.

 Dictionary entry details 

• POLYMERASE (noun)

Sense 1

Meaning:

An enzyme that catalyzes the formation of new DNA and RNA from an existing strand of DNA or RNA

Classified under:

Nouns denoting substances

Hypernyms ("polymerase" is a kind of...):

enzyme (any of several complex proteins that are produced by cells and act as catalysts in specific biochemical reactions)

Hyponyms (each of the following is a kind of "polymerase"):

DNA polymerase (the enzyme responsible for DNA replication)

RNA polymerase; transcriptase (the enzyme that copies DNA into RNA)

reverse transcriptase (a polymerase that catalyzes the formation of DNA using RNA as a template; found especially in retroviruses)

 Context examples 

This allele, which encodes protein AF-9, plays a role in modulation of transcription by RNA polymerase II (Gene Ontology/GO).

(MLLT3 wt Allele, NCI Thesaurus)

This allele, which encodes protein AF-17, is involved in the modulation of transcription by RNA polymerase II.

(MLLT6 wt Allele, NCI Thesaurus)

This allele, which encodes Myb proto-oncogene protein, plays a role in both the modulation of transcription by RNA polymerase II and differentiation of hematopoietic progenitor cells.

(MYB wt Allele, NCI Thesaurus)

This allele, which encodes Myb-related protein B, plays a role in proliferation, differentiation, cell survival, and in the regulation of transcription by RNA polymerase II.

(MYBL2 wt Allele, NCI Thesaurus)

This allele, which encodes caspase-9 protein, is involved in apoptosis via the cleavage and activation of both caspase-3 and poly (ADP-ribose) polymerase (PARP).

(CASP9 wt Allele, NCI Thesaurus)

This allele, which encodes caspase-7 protein, is involved in apoptosis via the cleavage and activation of both sterol regulatory element binding proteins and poly (ADP-ribose) polymerase (PARP).

(CASP7 wt Allele, NCI Thesaurus)

This agent also inhibits DNA polymerase, and has been shown to arrest leukemia cells in the G1-S transition phase of the cell cycle.

(Benzoylphenylurea, NCI Thesaurus)

Buciclovir is phosphorylated to its triphosphate form by HSV thymidine kinase in infected cells and acts as a specific inhibitor of the viral DNA polymerase.

(Buciclovir, NCI Thesaurus)

Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 2 (271 aa, ~31 kDa) is encoded by the human CTDSP2 gene.

(Carboxy-Terminal Domain RNA Polymerase II Polypeptide A Small Phosphatase 2, NCI Thesaurus)

This allele, which encodes caspase-6 protein, plays a role in the cleavage and activation of both lamins and poly (ADP-ribose) polymerase (PARP) during apoptosis.

(CASP6 wt Allele, NCI Thesaurus)