POLYCYSTIC KIDNEY DISEASE

Pronunciation (US):

(GB):

 Dictionary entry overview: What does polycystic kidney disease mean? 

• POLYCYSTIC KIDNEY DISEASE (noun)
  The noun POLYCYSTIC KIDNEY DISEASE has 1 sense:

1. kidney disease characterized by enlarged kidneys containing many cysts; often leads to kidney failure

  Familiarity information: POLYCYSTIC KIDNEY DISEASE used as a noun is very rare.

 Dictionary entry details 

• POLYCYSTIC KIDNEY DISEASE (noun)

Sense 1

Meaning:

Kidney disease characterized by enlarged kidneys containing many cysts; often leads to kidney failure

Classified under:

Nouns denoting stable states of affairs

Synonyms:

PKD; polycystic kidney disease

Hypernyms ("polycystic kidney disease" is a kind of...):

kidney disease; nephropathy; nephrosis; renal disorder (a disease affecting the kidneys)

 Context examples 

The MTOR gene is associated with polycystic kidney disease.

(MTOR wt Allele, NCI Thesaurus)

Mutations in the gene are associated with polycystic kidney disease autosomal dominant type 1.

(PKD1 wt Allele, NCI Thesaurus)

Alteration in the expression of this gene is associated with carcinoma of the prostate, polycystic kidney disease, polycystic liver disease, pituitary adenoma, acute promyelocytic leukemia, chronic lymphocytic leukemia and chronic myelogenous leukemia.

(MIR15A wt Allele, NCI Thesaurus)

This gene is involved in the regulation of gene expression and plays a potential tumor suppressor role in prostate carcinomas, various leukemias, pituitary adenoma, polycystic kidney disease and polycystic liver disease.

(MIR15A Gene, NCI Thesaurus)

Polycystic kidney disease inherited in an autosomal dominant pattern.

(Autosomal Dominant Polycystic Kidney Disease, NCI Thesaurus)

Polycystic kidney disease inherited in an autosomal recessive pattern.

(Autosomal Recessive Polycystic Kidney Disease, NCI Thesaurus)

Polycystic kidney disease (PKD) runs in families.

(Kidney Cysts, NIH: National Institute of Diabetes and Digestive and Kidney Diseases)