POINT MUTATION

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 Dictionary entry overview: What does point mutation mean? 

• POINT MUTATION (noun)
  The noun POINT MUTATION has 1 sense:

1. (genetics) a mutation due to an intramolecular reorganization of a gene

  Familiarity information: POINT MUTATION used as a noun is very rare.

 Dictionary entry details 

• POINT MUTATION (noun)

Sense 1

Meaning:

(genetics) a mutation due to an intramolecular reorganization of a gene

Classified under:

Nouns denoting natural events

Synonyms:

gene mutation; point mutation

Hypernyms ("point mutation" is a kind of...):

chromosomal mutation; genetic mutation; mutation ((genetics) any event that changes genetic structure; any alteration in the inherited nucleic acid sequence of the genotype of an organism)

Domain category:

genetic science; genetics (the branch of biology that studies heredity and variation in organisms)

 Context examples 

Any point mutation occuring within the protein-coding region of a gene, and which results in a retention of the reading frame of the encoded protein.

(Inframe Mutation, NCI Thesaurus)

A synthetic form of the K-ras protein containing any one of a number of point mutations at position 12 which is normally occupied by glycine (GLY).

(K-RAS GLY-12 Mutant Protein, NCI Thesaurus)

A point mutation involving the substitution of Cytosine (a pyrimidine base) for Adenosine (a purine base) in a DNA sequence from eukaryotic or prokaryotic organisms.

(Adenosine to Cytosine Transversion Abnormality, NCI Thesaurus)

Point mutations in the gene have been associated with ovarian serous carcinoma and ductal carcinoma of the breast.

(HOOK3 wt Allele, NCI Thesaurus)

A point mutation involving the substitution of Cytosine (a pyrimidine base) for Guanosine (a purine base) in a DNA sequence from eukaryotic or prokaryotic organisms.

(Guanosine to Cytosine Transversion Abnormality, NCI Thesaurus)

A point mutation involving the substitution of Thymidine (a pyrimidine base) for Guanosine (a purine base) in a DNA sequence from eukaryotic or prokaryotic organisms.

(Guanosine to Thymidine Transversion Abnormality, NCI Thesaurus)

A synthetic form of the K-ras protein containing a point mutation at position 12 (glycine to valine).

(K-RAS VAL-12 Mutant Protein, NCI Thesaurus)

A synthetic form of the K-ras protein containing a point mutation at position 12 (glycine to cysteine).

(KRAS CYS-12 Mutant Protein, NCI Thesaurus)

A point mutation that involves the substitution of a pyrimidine base for a different pyrimidine base or substitution of a purine base for a different purine base.

(Nucleotide Transition Abnormality, NCI Thesaurus)

A point mutation that involves the substitution of a pyrimidine base for a purine base or substitution of a purine base for a pyrimidine base.

(Nucleotide Transversion Abnormality, NCI Thesaurus)