PLASMINOGEN ACTIVATOR

Pronunciation (US):

(GB):

IPA (US):

 Dictionary entry overview: What does plasminogen activator mean? 

• PLASMINOGEN ACTIVATOR (noun)
  The noun PLASMINOGEN ACTIVATOR has 1 sense:

1. protease produced in the kidney that converts plasminogen to plasmin and so initiates fibrinolysis

  Familiarity information: PLASMINOGEN ACTIVATOR used as a noun is very rare.

 Dictionary entry details 

• PLASMINOGEN ACTIVATOR (noun)

Sense 1

Meaning:

Protease produced in the kidney that converts plasminogen to plasmin and so initiates fibrinolysis

Classified under:

Nouns denoting substances

Synonyms:

plasminogen activator; urokinase

Hypernyms ("plasminogen activator" is a kind of...):

peptidase; protease; proteinase; proteolytic enzyme (any enzyme that catalyzes the splitting of proteins into smaller peptide fractions and amino acids by a process known as proteolysis)

 Context examples 

Plasminogen activator inhibitor 1 (PAI1) and plasminogen activator inhibitor 2 (PAI2) inhibit cleavage of plasminogen by tissue-type plasminogen activator (tPA) or urokinase plasminogen activator (uPA).

(Fibrinolysis Pathway, NCI Thesaurus/BIOCARTA)

A measurement of the plasminogen activator inhibitor-1 in a biological specimen.

(Plasminogen Activator Inhibitor-1 Measurement, NCI Thesaurus/CDISC)

This allele, which encodes tissue-type plasminogen activator protein, is involved in the regulation of plasmin-mediated proteolysis via the conversion of the proenzyme plasminogen to plasmin.

(PLAT wt Allele, NCI Thesaurus)

A form of tissue plasminogen activator that is made in the laboratory.

(Activase, NCI Dictionary)

This allele, which encodes urokinase-type plasminogen activator protein, plays a role in the degradation of the extracellular matrix via activation of plasminogen.

(PLAU wt Allele, NCI Thesaurus)

The determination of the amount of plasminogen activator inhibitor-1 antigen present in a sample.

(Plasminogen Activator Inhibitor-1 Antigen Measurement, NCI Thesaurus)

Plasminogen activator inhibitor 2 (415 aa, ~47 kDa) is encoded by the human SERPINB2 gene.

(Plasminogen Activator Inhibitor 2, NCI Thesaurus)

A measurement of the plasminogen activator inhibitor-1 antigen in a biological specimen.

(Plasminogen Activator Inhibitor-1 Antigen Measurement, NCI Thesaurus/CDISC)

The determination of the amount of plasminogen activator inhibitor-1 present in a sample.

(Plasminogen Activator Inhibitor-1 Measurement, NCI Thesaurus)

Plasminogen activator inhibitor 1 (402 aa, ~45 kDa) is encoded by the human SERPINE1 gene.

(Plasminogen Activator Inhibitor 1, NCI Thesaurus)