PLASMIN

Pronunciation (US):

(GB):

 Dictionary entry overview: What does plasmin mean? 

• PLASMIN (noun)
  The noun PLASMIN has 1 sense:

1. an enzyme that dissolves the fibrin of blood clots

  Familiarity information: PLASMIN used as a noun is very rare.

 Dictionary entry details 

• PLASMIN (noun)

Sense 1

Meaning:

An enzyme that dissolves the fibrin of blood clots

Classified under:

Nouns denoting substances

Synonyms:

fibrinolysin; plasmin

Hypernyms ("plasmin" is a kind of...):

enzyme (any of several complex proteins that are produced by cells and act as catalysts in specific biochemical reactions)

Hyponyms (each of the following is a kind of "plasmin"):

plasminogen (an inactive form of plasmin that occurs in plasma and is converted to plasmin by organic solvents)

 Context examples 

Plasmin is a two-chain trypsin-like serine protease.

(Fibrinolysis Pathway, NCI Thesaurus/BIOCARTA)

A family of serine proteases that catalyze the proteolytic conversion of plasminogen to plasmin.

(Plasminogen Activator, NCI Thesaurus)

This protein plays a role in both cell adhesion and the modulation of plasmin activity.

(Plasminogen Activator Inhibitor 1, NCI Thesaurus)

This protein plays a role in the modulation of both plasmin activation and apoptosis.

(Plasminogen Activator Inhibitor 2, NCI Thesaurus)

Plasminogen Activator Interaction involves temporary non-covalent binding through intermolecular physical forces of attraction with heterogeneous group of widely expressed lysosomal and secreted serine proteases having fibrin-binding activity that convert plasminogen to fibrinolytic plasmin.

(Plasminogen Activator Interaction, NCI Thesaurus)

A recombinant therapeutic agent which is chemically identical to or similar to endogenous tissue plasminogen activator (tPA). tPA is a serine protease which converts plasminogen to plasmin, a fibrinolytic enzyme.

(Alteplase, NCI Thesaurus)

It directly inhibits proteolytic activity of plasmin, but higher doses are required than are needed to reduce plasmin formation.

(Aminocaproic Acid, NCI Thesaurus)

Proforms of NGF and BDNF are secreted and cleaved by plasmin serine protease and matrix metalloproteinases (MMP7, MMP3); proforms preferentially activate p75(NTR) to mediate apoptosis and mature forms activate TRK receptors to promote survival.

(Brain-Derived Neurotrophic Factor, NCI Thesaurus)

As a broad-spectrum serine protease inhibitor, aprotinin bovine competitively and reversibly inhibits the activity of a number of different esterases and proteases, including trypsin, chymotrypsin, kallikrein, plasmin, tissue plasminogen activator, and tissue and leukocytic proteinases, resulting in attenuation of the systemic inflammatory response (SIR), fibrinolysis, and thrombin generation.

(Aprotinin, NCI Thesaurus)

The removal of the clot is caused by plasmin cleavage of the fibrin monomers into soluble fibrin degradation products.

(Fibrinolysis Pathway, NCI Thesaurus/BIOCARTA)