PLASMID

Pronunciation (US):

(GB):

 Dictionary entry overview: What does plasmid mean? 

• PLASMID (noun)
  The noun PLASMID has 1 sense:

1. a small cellular inclusion consisting of a ring of DNA that is not in a chromosome but is capable of autonomous replication

  Familiarity information: PLASMID used as a noun is very rare.

 Dictionary entry details 

• PLASMID (noun)

Sense 1

Meaning:

A small cellular inclusion consisting of a ring of DNA that is not in a chromosome but is capable of autonomous replication

Classified under:

Nouns denoting natural objects (not man-made)

Synonyms:

plasmid; plasmid DNA

Hypernyms ("plasmid" is a kind of...):

cellular inclusion; inclusion; inclusion body (any small intracellular body found within another (characteristic of certain diseases))

 Context examples 

Upon administration, NY-ESO-1 plasmid DNA cancer vaccine may stimulate the host immune system to mount a cytotoxic T lymphocyte (CTL) response against tumor cells expressing the NY-ESO-1 antigen, resulting in tumor cell lysis.

(NY-ESO-1 Plasmid DNA Cancer Vaccine, NCI Thesaurus)

Usually applied to specific genes or to plasmids within a bacterium.

(Copy Number, NCI Thesaurus)

A plasmid DNA vaccine encoding the mouse tumor associated antigen tyrosinase-related protein-2 (TYRP2) with potential immunostimulating and antineoplastic activities.

(Murine TYRP2 Plasmid DNA Vaccine, NCI Thesaurus)

A formulation composed of DOTAP:cholesterol liposome nanoparticles complexed with the plasmid C-VISA BiKDD, with potential antineoplastic activity.

(C-VISA BikDD:Liposome, NCI Thesaurus)

Upon administration, CYL-02 plasmid DNA expresses DCK::UMK fusion protein that converts gemcitabine into its toxic phosphorylated metabolite.

(CYL-02 Plasmid DNA, NCI Thesaurus)

Upon intratumoral electrotransfer of plasmid encoding AMEP, AMEP binds to cellular integrin receptors alpha-v-beta-3 (avb3) and alpha-5-beta-1 (a5b1), which are upregulated on activated endothelial cells and a variety of tumor cells.

(Plasmid Encoding Antiangiogenic Metargidin Peptide, NCI Thesaurus)

Finally, they inserted a plasmid—a circular piece of DNA—that contained one d5SICS-dNaM pair into the cells.

(Expanding the Genetic Alphabet, NIH)

Cosmid vector can hold larger pieces of foreign DNA (inserts) than plasmids.

(Cosmid Vector, NCI Thesaurus)

The innards include plasmids, which are loops of DNA.

(Test for life-threatening nutrient deficit is made from bacteria entrails, National Science Foundation)

The copies are inserted into a bacterial plasmid or bacteriophage vector.

(cDNA Library Construction, NCI Thesaurus)