PLAQUE

Pronunciation (US):

(GB):

IPA (US):

 Dictionary entry overview: What does plaque mean? 

• PLAQUE (noun)
  The noun PLAQUE has 2 senses:

1. (pathology) a small abnormal patch on or inside the body

2. a memorial made of brass

  Familiarity information: PLAQUE used as a noun is rare.

 Dictionary entry details 

• PLAQUE (noun)

Sense 1

Meaning:

(pathology) a small abnormal patch on or inside the body

Classified under:

Nouns denoting body parts

Hypernyms ("plaque" is a kind of...):

dapple; fleck; maculation; patch; speckle; spot (a small contrasting part of something)

Domain category:

pathology (the branch of medical science that studies the causes and nature and effects of diseases)

Hyponyms (each of the following is a kind of "plaque"):

amyloid plaque; amyloid protein plaque (a plaque consisting of tangles of amyloid protein in nervous tissue (a pathological mark of Alzheimer's disease))

arterial plaque (a fatty deposit inside an arterial wall; characteristic of atherosclerosis)

bacterial plaque; dental plaque (a film of mucus and bacteria deposited on the teeth that encourages the development of dental caries)

Sense 2

Meaning:

A memorial made of brass

Classified under:

Nouns denoting man-made objects

Synonyms:

brass; memorial tablet; plaque

Hypernyms ("plaque" is a kind of...):

memorial; monument (a structure erected to commemorate persons or events)

 Context examples 

The plaques are abnormal clumps of toxic fragments of the protein beta-amyloid.

(Human Cells Model Alzheimer’s Disease, NIH)

They did find that treatment increased the build-up of plaque in the artery that supplies blood to the heart.

(Hormone treatment studied in older men, NIH)

Using an imaging procedure, the researchers found that the quantity of plaque was 30 percent higher in the alpha-Gal sensitized patients than in the non-sensitized patients.

(Researchers have found a link between allergen in red meat and heart disease, National Institutes of Health)

Patients present with a localized psoriasiform or hyperkeratotic patch or plaque, usually in the extremities.

(Pagetoid Reticulosis, NCI Thesaurus)

It has an indolent clinical course and may be associated with skin plaques.

(Acquired Progressive Lymphangioma, NCI Thesaurus)

Medicines can slow the progress of plaque buildup.

(Atherosclerosis, NIH: National Heart, Lung, and Blood Institute)

If the development of amyloid plaques is responsible for neurodegeneration in Alzheimer's disease, reduction of beta-amyloid formation may prevent the development and progression of disease symptoms.

(Amyloid Beta-Peptide Pathway, NCI Thesaurus/BIOCARTA)

A peripheral (mature) T-cell lymphoma presenting in the skin with patches/plaques.

(Mycosis fungoides, NCI Thesaurus/WHO)

A peripheral (mature) T-cell lymphoma presenting in the skin with patches/plaques and it is characterized by epidermal and dermal infiltration of small to medium-sized T-cells with cerebriform nuclei.

(Mycosis Fungoides (Working Formulation), NCI Thesaurus)

This happens when plaque builds up on the walls of the arteries that supply blood to the arms and legs.

(Peripheral Arterial Disease, NIH: National Heart, Lung, and Blood Institute)