PIPERACILLIN

Pronunciation (US):

(GB):

 Dictionary entry overview: What does piperacillin mean? 

• PIPERACILLIN (noun)
  The noun PIPERACILLIN has 1 sense:

1. a synthetic type of penicillin antibiotic (trade name Pipracil) used for moderate to severe infections

  Familiarity information: PIPERACILLIN used as a noun is very rare.

 Dictionary entry details 

• PIPERACILLIN (noun)

Sense 1

Meaning:

A synthetic type of penicillin antibiotic (trade name Pipracil) used for moderate to severe infections

Classified under:

Nouns denoting man-made objects

Synonyms:

piperacillin; Pipracil

Hypernyms ("piperacillin" is a kind of...):

penicillin (any of various antibiotics obtained from Penicillium molds (or produced synthetically) and used in the treatment of various infections and diseases)

 Context examples 

Piperacillin is a synthetic penicillin; tazobactam enhances the effectiveness of piperacillin.

(Piperacillin-tazobactam, NCI Dictionary)

A combination formulation of the antibiotic piperacillin and the beta-lactamase inhibitor tazobactam with antibacterial activity.

(Piperacillin-tazobactam, NCI Thesaurus)

Piperacillin binds to and inactivates penicillin-binding proteins (PBPs), enzymes located on the inner membrane of the bacterial cell wall, resulting in the weakening of the bacterial cell wall and cell lysis.

(Piperacillin Sodium, NCI Thesaurus)

Piperacillin binds to penicillin binding proteins (PBP), the enzymes that catalyze the synthesis of peptidoglycan, a critical component of the bacterial cell wall.

(Piperacillin, NCI Thesaurus)

Piperacillin binds to penicillin binding proteins (PBP) located on the inner membrane of the bacterial cell wall, thereby interfering with the cross-linking of peptidoglycan chains necessary for bacterial cell wall strength and rigidity.

(Piperacillin Anhydrous, NCI Thesaurus)

They chose from 3 distinct subclasses of β-lactam compounds that target different aspects of the cell wall synthesis machinery in MRSA: meropenem, piperacillin, and tazobactam (ME/PI/TZ).

(Antibiotic Combinations May Combat MRSA Infections, NIH)

The sodium salt of piperacillin, a broad-spectrum semisynthetic, ampicillin-derived ureidopenicillin antibiotic with bactericidal activity.

(Piperacillin Sodium, NCI Thesaurus)

Tazobactam, a penicillanic acid sulfone derivative, irreversibly binds to and inhibits bacterial beta-lactamase at or near its active site, thereby preventing the destruction of the beta-lactamase susceptible piperacillin by this bacterial enzyme.

(Piperacillin-tazobactam, NCI Thesaurus)

The anhydrous form of piperacillin, a broad-spectrum semisynthetic ureidopenicillin antibiotic.

(Piperacillin Anhydrous, NCI Thesaurus)

Piperacillin, a broad-spectrum, semisynthetic penicillin, binds to and inactivates penicillin-binding proteins (PBP) located on the inner membrane of the bacterial cell wall, thereby interfering with the cross-linking of peptidoglycan chains necessary for bacterial cell wall strength and rigidity.

(Piperacillin-tazobactam, NCI Thesaurus)