PHENOTYPE

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 Dictionary entry overview: What does phenotype mean? 

• PHENOTYPE (noun)
  The noun PHENOTYPE has 1 sense:

1. what an organism looks like as a consequence of the interaction of its genotype and the environment

  Familiarity information: PHENOTYPE used as a noun is very rare.

 Dictionary entry details 

• PHENOTYPE (noun)

Sense 1

Meaning:

What an organism looks like as a consequence of the interaction of its genotype and the environment

Classified under:

Nouns denoting attributes of people and objects

Hypernyms ("phenotype" is a kind of...):

composition; constitution; make-up; makeup; physical composition (the way in which someone or something is composed)

Derivation:

phenotypic; phenotypical (of or relating to or constituting a phenotype)

 Context examples 

Overexpression of specific Src kinases is also associated with the imatinib-resistant CML phenotype.

(Bosutinib, NCI Thesaurus)

This agent may reverse the malignant phenotype of H-Ras-transformed cells and has been shown to be active against tumor cells with and without Ras mutations.

(BMS-214662, NCI Thesaurus)

Biomarkers include but not limited to such phenotypic parameters as specific enzyme or hormone concentration, specific gene phenotype, presence or absence of biological substances.

(Biomarker, NCI Thesaurus)

NEO is widely used in genetic research because of the easily selectable phenotype.

(NEO Gene, NCI Thesaurus)

Encoded by human BCAR2 Gene, Breast Cancer Anti-Estrogen Resistance 2 Protein is similar to gamma-butyrobetaine 2-oxoglutarate dioxygenase (C. elegans, Drosophila) and likely responsible for development of an anti-estrogen-resistant phenotype.

(Breast Cancer Anti-Estrogen Resistance 2 Protein, NCI Thesaurus)

Processes that create, promote, and maintain a differentiated cellular phenotype.

(Cell Maturation, NCI Thesaurus)

Several allelic variants of the CYP2C8 gene contribute to the poor metabolizer phenotype.

(CYP2C8 wt Allele, NCI Thesaurus)

Individuals with a high-inducibility phenotype, who exhibit elevated CYP1A1 gene expression in response to PAHs, may be at greater risk for cigarette smoke-induced bronchogenic carcinoma.

(CYP1A1 wt Allele, NCI Thesaurus)

A phenotype whereby a subset of tumors are characterized by the simultaneous hypermethylation of multiple promoter-associated CpG islands.

(CpG Island Methylator Phenotype, NCI Thesaurus)

This allele, which encodes breast carcinoma amplified sequence 1 protein, plays a role in tumorigenesis and is associated with more aggressive tumor phenotypes when altered.

(BCAS1 wt Allele, NCI Thesaurus)