PHASE TRANSITION

Pronunciation (US):

(GB):

IPA (US):

 Dictionary entry overview: What does phase transition mean? 

• PHASE TRANSITION (noun)
  The noun PHASE TRANSITION has 1 sense:

1. a change from one state (solid or liquid or gas) to another without a change in chemical composition

  Familiarity information: PHASE TRANSITION used as a noun is very rare.

 Dictionary entry details 

• PHASE TRANSITION (noun)

Sense 1

Meaning:

A change from one state (solid or liquid or gas) to another without a change in chemical composition

Classified under:

Nouns denoting natural processes

Synonyms:

phase change; phase transition; physical change; state change

Hypernyms ("phase transition" is a kind of...):

action; activity; natural action; natural process (a process existing in or produced by nature (rather than by the intent of human beings))

Hyponyms (each of the following is a kind of "phase transition"):

freeze; freezing (the withdrawal of heat to change something from a liquid to a solid)

liquefaction (the conversion of a solid or a gas into a liquid)

melt; melting; thaw; thawing (the process whereby heat changes something from a solid to a liquid)

evaporation; vapor; vaporisation; vaporization; vapour (the process of becoming a vapor)

 Context examples 

A protein family that is synthesized during the G1 phase of the cell cycle and drives the G1/S phase transition through the positive regulation of cyclin-dependent kinase activity.

(Cyclin D, NCI Thesaurus)

This allele, which encodes cell division cycle 7-related protein kinase, is involved in the regulation of both chromosome replication and the G1/S phase transition for the cell cycle.

(CDC7 wt Allele, NCI Thesaurus)

Association with the tumor suppressor Rb represses E2F-1 activity, and this repression is relieved when the cdk2/cyclin E complex at the G1 to S phase transition phosphorylates Rb.

(E2F1 Degradation Pathway, NCI Thesaurus/BIOCARTA)

This allele is essential for the transit of the cell through the G1/S phase transition.

(CDK2 wt Allele, NCI Thesaurus)

A protein family that is synthesized during the G1 phase of the cell cycle and drives the G1/S phase transition through the positive regulation of cyclin-dependent kinase 2 activity.

(Cyclin E, NCI Thesaurus)

Inhibition of Rb phosphorylation prevents CDK-mediated G1-S phase transition, thereby arresting the cell cycle in the G1 phase, suppressing DNA synthesis and inhibiting cancer cell growth.

(CDK4/6 Dual Inhibitor LY2835219, NCI Thesaurus)

CDK4 inhibitor P1446A-05 specifically inhibits CDK4-mediated G1-S phase transition, arresting cell cycling and inhibiting cancer cell growth.

(CDK4 Inhibitor P1446A-05, NCI Thesaurus)

Treatment of cells with this agent results in inhibition of downstream signal transduction events and cell cycle regulatory pathways; arrest at the G1-S (Gap 1/DNA synthesis)-phase transition of the cell division cycle; and ultimately decreased cellular proliferation.

(Neratinib, NCI Thesaurus)