PHASE III

Pronunciation (US):

(GB):

 Dictionary entry overview: What does phase III mean? 

• PHASE III (noun)
  The noun PHASE III has 1 sense:

1. a large clinical trial of a treatment or drug that in phase I and phase II has been shown to be efficacious with tolerable side effects; after successful conclusion of these clinical trials it will receive formal approval from the FDA

  Familiarity information: PHASE III used as a noun is very rare.

 Dictionary entry details 

• PHASE III (noun)

Sense 1

Meaning:

A large clinical trial of a treatment or drug that in phase I and phase II has been shown to be efficacious with tolerable side effects; after successful conclusion of these clinical trials it will receive formal approval from the FDA

Classified under:

Nouns denoting acts or actions

Synonyms:

phase III; phase III clinical trial

Hypernyms ("phase III" is a kind of...):

clinical test; clinical trial (a rigorously controlled test of a new drug or a new invasive medical device on human subjects; in the United States it is conducted under the direction of the FDA before being made available for general clinical use)

 Context examples 

Often they are designed to study side effects that may have become apparent after the phase III study was completed.

(phase IV trial, NCI Thesaurus)

Phase IV trials are done using thousands of people after a treatment has been approved and marketed, to check for side effects that were not seen in the phase III trial.

(Clinical trial phase, NCI Dictionary)

After a treatment has been approved and is being marketed, it is studied in a phase IV trial to evaluate side effects that were not apparent in the phase III trial.

(phase IV trial, NCI Dictionary)

In most cases, studies move into phase III only after a treatment seems to work in phases I and II.

(phase III trial, NCI Dictionary)