PEPTIDE BOND

Pronunciation (US):

(GB):

IPA (US):

 Dictionary entry overview: What does peptide bond mean? 

• PEPTIDE BOND (noun)
  The noun PEPTIDE BOND has 1 sense:

1. the primary linkage of all protein structures; the chemical bond between the carboxyl groups and amino groups that unites a peptide

  Familiarity information: PEPTIDE BOND used as a noun is very rare.

 Dictionary entry details 

• PEPTIDE BOND (noun)

Sense 1

Meaning:

The primary linkage of all protein structures; the chemical bond between the carboxyl groups and amino groups that unites a peptide

Classified under:

Nouns denoting natural phenomena

Synonyms:

peptide bond; peptide linkage

Hypernyms ("peptide bond" is a kind of...):

bond; chemical bond (an electrical force linking atoms)

 Context examples 

A gene that encodes an enzyme that is capable of hydrolyzing the peptide bonds found between amino acids in proteins.

(Peptidase Gene, NCI Thesaurus)

The sequential formation of peptide bonds between amino acids

(Peptide Synthesis, NCI Thesaurus)

The binding interferes with peptidyl transferase activity, thereby prevents transfer of amino acids to the growing peptide chains and blocks peptide bond formation.

(Chloramphenicol, NCI Thesaurus)

A class of enzymes that catalyze the hydrolysis of peptide bonds in the interior of a polypeptide chain or protein molecule.

(Endopeptidase, NCI Thesaurus)

A gene that encodes a proteolytic enzyme that depends on a metal ion to catalyze peptide bond hydrolysis.

(Metalloproteinase Gene, NCI Thesaurus)

A proteolytic enzyme that uses a metal ion, usually zinc, to catalyze the hydrolysis of peptide bonds.

(Metalloproteinase, NCI Thesaurus)

Family of enzymes which use a metal ion in the catalytic process and preferentially cleave the Gln-Gly peptide bond.

(Metalloproteinase, NIH CRISP Thesaurus)

Ubiquitin is coupled to protein by a peptide bond between the ubiquitin C-terminal glycine and protein lysine alpha-amino groups.

(E3 Ubiquitin Ligase, NCI Thesaurus)

Aspartyl Proteases (Aspartic Endopeptidases) have an acidic residue (aspartate) involved in the catalytic process, have a pH optimum below 5 and catalyze the cleavage of internal peptide bonds in a polypeptide or protein.

(Aspartyl Protease, NCI Thesaurus)

As a reagent for peptide mapping and amino acid sequence analysis, cyanogen bromide hydrolyzes peptide bonds at methionine residues in peptides and proteins.

(Cyanogen Bromide, NCI Thesaurus)