PEMPHIGUS

Pronunciation (US):

(GB):

 Dictionary entry overview: What does pemphigus mean? 

• PEMPHIGUS (noun)
  The noun PEMPHIGUS has 1 sense:

1. a skin disease characterized by large thin-walled blisters (bullae) arising from normal skin or mucous membrane

  Familiarity information: PEMPHIGUS used as a noun is very rare.

 Dictionary entry details 

• PEMPHIGUS (noun)

Sense 1

Meaning:

A skin disease characterized by large thin-walled blisters (bullae) arising from normal skin or mucous membrane

Classified under:

Nouns denoting stable states of affairs

Hypernyms ("pemphigus" is a kind of...):

autoimmune disease; autoimmune disorder (any of a large group of diseases characterized by abnormal functioning of the immune system that causes your immune system to produce antibodies against your own tissues)

disease of the skin; skin disease; skin disorder (a disease affecting the skin)

Meronyms (parts of "pemphigus"):

acantholysis (a breakdown of a cell layer in the epidermis (as in pemphigus))

Derivation:

pemphigous (of or relating to or manifesting pemphigus)

 Context examples 

The treatment of pemphigus and pemphigoid is the same: one or more medicines to control symptoms.

(Pemphigus, NIH: National Institute of Arthritis and Musculoskeletal and Skin Diseases)

The team tested the engineered T cells in a mouse model of pemphigus vulgaris.

(Approach targets autoimmunity, NIH)

An autosomal dominant disorder characterized by a history of multiple relapses and remissions of pemphigus lesions.

(Familial Benign Pemphigus, NCI Thesaurus)

A rare autoimmune blistering skin disorder that resembles pemphigus but is histologically and clinically distinguishable by lack of evidence of acantholysis and a generally benign course.

(Pemphigoid, NCI Thesaurus)

Doctors diagnose pemphigus with a physical exam, a biopsy, and blood tests.

(Pemphigus, NIH: National Institute of Arthritis and Musculoskeletal and Skin Diseases)

The team showed in laboratory experiments that human T cells engineered to express portions of Dsg3 killed anti-Dsg3 B cells derived from people with pemphigus vulgaris.

(Approach targets autoimmunity, NIH)

But some people's genes put them more at risk for pemphigus.

(Pemphigus, NIH: National Institute of Arthritis and Musculoskeletal and Skin Diseases)

The most common type of pemphigus is pemphigus vulgaris.

(Approach targets autoimmunity, NIH)

Pemphigus does not spread from person to person.

(Pemphigus, NIH: National Institute of Arthritis and Musculoskeletal and Skin Diseases)

Pemphigus can be treated with drugs that suppress the immune system or that specifically deplete B cells.

(Approach targets autoimmunity, NIH)